Hydrocortisone and Hepatic failure - a phase IV clinical study of FDA data

Summary:

Hepatic failure is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Psoriasis.

The phase IV clinical study analyzes which people have Hepatic failure when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Hepatic failure?

Hepatic failure (liver failure) is found to be associated with 1,539 drugs and 1,894 conditions by eHealthMe. Check the latest studies of Hepatic failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 184 people (0.46%) have Hepatic failure.

Could Hydrocortisone cause Hepatic failure?

Among these 184 people:

How long have people been on Hydrocortisone when they have Hepatic failure? *

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What is the gender of people who have Hepatic failure when taking Hydrocortisone? *

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What is the age of people who have Hepatic failure when taking Hydrocortisone? *

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* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Hepatic failure?

- Check whether Hepatic failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Hydrocortisone (40,425 reports)

Hepatic failure treatments and more:

Hepatic failure (44,058 reports)

How severe was Hepatic failure and when was it recovered:

Hepatic failure in Hydrocortisone

Expand to all the drugs that have ingredients of hydrocortisone:

Hepatic failure and drugs with ingredients of hydrocortisone (233 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic failure:

Hepatic failure (1,539 drugs)

Browse all the conditions that are associated with Hepatic failure:

Hepatic failure (1,894 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.