Hydrocortisone and Lichen planus - a phase IV clinical study of FDA data

Summary:

Lichen planus is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Gabapentin, and have Psoriasis.

The phase IV clinical study analyzes which people have Lichen planus when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,426 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Lichen planus?

Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash) is found to be associated with 249 drugs and 559 conditions by eHealthMe. Check the latest studies of Lichen planus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 17 people (0.04%) have Lichen planus.

Could Hydrocortisone cause Lichen planus?

Among these 17 people:

How long have people been on Hydrocortisone when they have Lichen planus? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lichen planus when taking Hydrocortisone? *

  • female: 56.25 %
  • male: 43.75 %

What is the age of people who have Lichen planus when taking Hydrocortisone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 30.77 %
  • 30-39: 0.0 %
  • 40-49: 15.38 %
  • 50-59: 7.69 %
  • 60+: 46.15 %

What are other drugs people take besides Hydrocortisone? *

  1. Omeprazole: 5 people, 29.41%
  2. Gabapentin: 5 people, 29.41%
  3. Adcal: 4 people, 23.53%
  4. Topiramate: 4 people, 23.53%
  5. Cosentyx: 4 people, 23.53%
  6. Clarithromycin: 4 people, 23.53%
  7. Ramipril: 4 people, 23.53%
  8. Magnesium Sulfate: 4 people, 23.53%
  9. Tylenol: 4 people, 23.53%
  10. Heparin: 4 people, 23.53%

What are other side effects people have besides Lichen planus? *

  1. Fatigue (feeling of tiredness): 7 people, 41.18%
  2. Nausea (feeling of having an urge to vomit): 6 people, 35.29%
  3. Diarrhea: 5 people, 29.41%
  4. Nausea And Vomiting: 5 people, 29.41%
  5. Vision Blurred: 5 people, 29.41%
  6. Hypotension (abnormally low blood pressure): 5 people, 29.41%
  7. Insomnia (sleeplessness): 5 people, 29.41%
  8. Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 4 people, 23.53%
  9. Neurological Symptom (symptoms of nervous system disease): 4 people, 23.53%
  10. Photopsia (presence of perceived flashes of light): 4 people, 23.53%

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 7 people, 41.18%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 29.41%
  3. Pain: 4 people, 23.53%
  4. High Blood Pressure: 4 people, 23.53%
  5. Ill-Defined Disorder: 3 people, 17.65%
  6. Urinary Tract Infection: 1 person, 5.88%
  7. Lymph Node Tuberculosis: 1 person, 5.88%
  8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 5.88%
  9. Depression: 1 person, 5.88%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Lichen planus?

- Check whether Lichen planus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Lichen planus treatments and more:

How severe was Lichen planus and when was it recovered:

Expand to all the drugs that have ingredients of hydrocortisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lichen planus:

Browse all the conditions that are associated with Lichen planus:


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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