Hydrocortisone and Sinus arrhythmia - a phase IV clinical study of FDA data

Summary:

Sinus arrhythmia is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Tylenol, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Sinus arrhythmia when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Sinus arrhythmia?

Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle) is found to be associated with 361 drugs and 419 conditions by eHealthMe. Check the latest studies of Sinus arrhythmia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 20 people (0.05%) have Sinus arrhythmia.

Could Hydrocortisone cause Sinus arrhythmia?

Among these 20 people:

How long have people been on Hydrocortisone when they have Sinus arrhythmia? *

What is the gender of people who have Sinus arrhythmia when taking Hydrocortisone? *

female: 40 %
male: 60 %

What is the age of people who have Sinus arrhythmia when taking Hydrocortisone? *

What are other drugs people take besides Hydrocortisone? *

What are other side effects people have besides Sinus arrhythmia? *

Pain: 16 people, 80.00%
Stress And Anxiety: 16 people, 80.00%
Injury: 15 people, 75.00%
High Blood Pressure: 13 people, 65.00%
Deformity (disfigurement): 13 people, 65.00%
Inflammation: 10 people, 50.00%
Chest Pain: 10 people, 50.00%
Fistula (an abnormal connection or passageway between two): 10 people, 50.00%
Osteonecrosis Of Jaw (death of bone of jaw): 10 people, 50.00%
Pneumonia: 10 people, 50.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 50.00%
Depression: 6 people, 30.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 5.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.00%
Prostate Cancer: 1 person, 5.00%
Proctalgia (pain in the rectum): 1 person, 5.00%
Pain: 1 person, 5.00%
Nausea (feeling of having an urge to vomit): 1 person, 5.00%
Muscle Spasms (muscle contraction): 1 person, 5.00%
Metastasis (spreadable cancer to other organ from origin): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Sinus arrhythmia?

- Check whether Sinus arrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Hydrocortisone (40,425 reports)

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus arrhythmia:

Sinus arrhythmia (361 drugs)

Browse all the conditions that are associated with Sinus arrhythmia:

Sinus arrhythmia (419 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.