Hydrocortisone and Sinus bradycardia - a phase IV clinical study of FDA data

Summary:

Sinus bradycardia is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ceftriaxone, and have Prostate cancer.

The phase IV clinical study analyzes which people have Sinus bradycardia when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Sinus bradycardia?

Sinus bradycardia (an unusually slow heartbeat due to heart disease) is found to be associated with 904 drugs and 1,053 conditions by eHealthMe. Check the latest studies of Sinus bradycardia.



On Aug, 04, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 62 people (0.16%) have Sinus bradycardia.

Could Hydrocortisone cause Sinus bradycardia?

Among these 62 people:

How long have people been on Hydrocortisone when they have Sinus bradycardia? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sinus bradycardia when taking Hydrocortisone? *

  • female: 54.24 %
  • male: 45.76 %

What is the age of people who have Sinus bradycardia when taking Hydrocortisone? *

  • 0-1: 1.72 %
  • 2-9: 3.45 %
  • 10-19: 3.45 %
  • 20-29: 3.45 %
  • 30-39: 3.45 %
  • 40-49: 17.24 %
  • 50-59: 15.52 %
  • 60+: 51.72 %

What are other drugs people take besides Hydrocortisone? *

  1. Ceftriaxone: 14 people, 22.58%
  2. Simvastatin: 12 people, 19.35%
  3. Furosemide: 12 people, 19.35%
  4. Acetaminophen: 11 people, 17.74%
  5. Lipitor: 11 people, 17.74%
  6. Allopurinol: 10 people, 16.13%
  7. Diazepam: 10 people, 16.13%
  8. Fish Oil: 10 people, 16.13%
  9. Hydrochlorothiazide: 10 people, 16.13%
  10. Propylthiouracil: 10 people, 16.13%

What are other side effects people have besides Sinus bradycardia? *

  1. Weight Decreased: 14 people, 22.58%
  2. Fatigue (feeling of tiredness): 13 people, 20.97%
  3. Fall: 13 people, 20.97%
  4. Atrioventricular Block First Degree (heart block first degree): 12 people, 19.35%
  5. Fever: 12 people, 19.35%
  6. Oedema Peripheral (superficial swelling): 11 people, 17.74%
  7. Tooth Abscess (pus formation in tooth): 11 people, 17.74%
  8. Wound: 11 people, 17.74%
  9. Cardiac Arrest: 11 people, 17.74%
  10. Blood Urea Increased: 11 people, 17.74%

What are the existing conditions these people have? *

  1. Prostate Cancer: 10 people, 16.13%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 11.29%
  3. Thyrotoxic Crisis (a life threatening condition due to excess secretion of thyroid hormone): 5 people, 8.06%
  4. Sedation: 3 people, 4.84%
  5. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 4.84%
  6. Adrenocortical Insufficiency Acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones): 3 people, 4.84%
  7. Septic Shock (shock due to blood infection): 3 people, 4.84%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 4.84%
  9. Respiratory Disorder (respiratory disease): 2 people, 3.23%
  10. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Sinus bradycardia?

- Check whether Sinus bradycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Sinus bradycardia treatments and more:

How severe was Sinus bradycardia and when was it recovered:

Expand to all the drugs that have ingredients of hydrocortisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus bradycardia:

Browse all the conditions that are associated with Sinus bradycardia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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