Hydrocortisone and Squamous cell carcinoma - a phase IV clinical study of FDA data

Summary:

Squamous cell carcinoma is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Squamous cell carcinoma when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Squamous cell carcinoma?

Squamous cell carcinoma (a cancer of a kind of epithelial cell) is found to be associated with 814 drugs and 895 conditions by eHealthMe. Check the latest studies of Squamous cell carcinoma.



On Jul, 16, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 52 people (0.13%) have Squamous cell carcinoma.

Could Hydrocortisone cause Squamous cell carcinoma?

Among these 52 people:

How long have people been on Hydrocortisone when they have Squamous cell carcinoma? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Squamous cell carcinoma when taking Hydrocortisone? *

  • female: 53.19 %
  • male: 46.81 %

What is the age of people who have Squamous cell carcinoma when taking Hydrocortisone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 25.0 %
  • 60+: 65.91 %

What are other drugs people take besides Hydrocortisone? *

  1. Zometa: 19 people, 36.54%
  2. Acetaminophen: 18 people, 34.62%
  3. Morphine: 18 people, 34.62%
  4. Decadron: 16 people, 30.77%
  5. Prednisone: 15 people, 28.85%
  6. Neurontin: 15 people, 28.85%
  7. Aspirin: 14 people, 26.92%
  8. Aredia: 13 people, 25.00%
  9. Lorazepam: 13 people, 25.00%
  10. Dexamethasone: 12 people, 23.08%

What are other side effects people have besides Squamous cell carcinoma? *

  1. Weight Decreased: 21 people, 40.38%
  2. Anaemia (lack of blood): 21 people, 40.38%
  3. Fatigue (feeling of tiredness): 21 people, 40.38%
  4. Osteomyelitis (infection of bone): 21 people, 40.38%
  5. Bone Disorder: 19 people, 36.54%
  6. Pain In Jaw: 19 people, 36.54%
  7. Pain: 16 people, 30.77%
  8. Pneumonia: 15 people, 28.85%
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 15 people, 28.85%
  10. Atelectasis (partial or complete collapse of the lung): 15 people, 28.85%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 13 people, 25.00%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 17.31%
  3. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 11.54%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 7.69%
  5. Sleep Disorder: 3 people, 5.77%
  6. High Blood Pressure: 3 people, 5.77%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 3.85%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 3.85%
  9. Depression: 2 people, 3.85%
  10. Diabetes: 2 people, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Squamous cell carcinoma?

- Check whether Squamous cell carcinoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Squamous cell carcinoma treatments and more:

How severe was Squamous cell carcinoma and when was it recovered:

Expand to all the drugs that have ingredients of hydrocortisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Squamous cell carcinoma:

Browse all the conditions that are associated with Squamous cell carcinoma:


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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