Hydrocortone and Liver disorder - a phase IV clinical study of FDA data

Summary:

Liver disorder is reported as a side effect among people who take Hydrocortone (hydrocortisone acetate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Itching.

The phase IV clinical study analyzes which people have Liver disorder when taking Hydrocortone. It is created by eHealthMe based on reports of 785 people who have side effects when taking Hydrocortone from the FDA, and is updated regularly.

What is Hydrocortone?

Hydrocortone has active ingredients of hydrocortisone acetate. It is often used in pain. eHealthMe is studying from 912 Hydrocortone users. Check the latest studies of Hydrocortone.

What is Liver disorder?

Liver disorder (liver diseases) is found to be associated with 1,734 drugs and 2,047 conditions by eHealthMe. Check the latest studies of Liver disorder.

On Aug, 05, 2026

785 people reported to have side effects when taking Hydrocortone.
Among them, 15 people (1.91%) have Liver disorder.

Could Hydrocortone cause Liver disorder?

Among these 15 people:

How long have people been on Hydrocortone when they have Liver disorder? *

What is the gender of people who have Liver disorder when taking Hydrocortone? *

female: 26.67 %
male: 73.33 %

What is the age of people who have Liver disorder when taking Hydrocortone? *

What are other drugs people take besides Hydrocortone? *

Methotrexate: 4 people, 26.67%
Lexapro: 3 people, 20.00%
Fluocinolone Acetonide: 3 people, 20.00%
Lopressor: 3 people, 20.00%
Vancomycin: 3 people, 20.00%
Amikacin Sulfate: 3 people, 20.00%
Atarax: 3 people, 20.00%
Raptiva: 3 people, 20.00%
Fosamax: 3 people, 20.00%
Folic Acid: 3 people, 20.00%

What are other side effects people have besides Liver disorder? *

Alanine Aminotransferase Increased: 4 people, 26.67%
Blood Lactate Dehydrogenase Increased: 4 people, 26.67%
Diarrhea: 4 people, 26.67%
Aspartate Aminotransferase Increased: 4 people, 26.67%
Febrile Neutropenia (fever with reduced white blood cells): 4 people, 26.67%
Gamma-Glutamyltransferase Increased: 3 people, 20.00%
White Blood Cell Count Decreased: 3 people, 20.00%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 20.00%
Renal Impairment (severely reduced kidney function): 3 people, 20.00%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 20.00%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 3 people, 20.00%
Itching: 3 people, 20.00%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 13.33%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 13.33%
Inappropriate Antidiuretic Hormone Secretion: 2 people, 13.33%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 13.33%
Venipuncture: 1 person, 6.67%
Herpes Virus Infection: 1 person, 6.67%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 6.67%
Bone Marrow Conditioning Regimen: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortone and have Liver disorder?

- Check whether Liver disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortone:

Hydrocortone (912 reports)

Liver disorder treatments and more:

Liver disorder (57,384 reports)

Browse all side effects of Hydrocortone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver disorder:

Liver disorder (1,734 drugs)

Browse all the conditions that are associated with Liver disorder:

Liver disorder (2,047 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone acetate (the active ingredients of Hydrocortone) and Hydrocortone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.