Hydrodiuril and Urinary retention - a phase IV clinical study of FDA data

Summary:

Urinary retention is reported as a side effect among people who take Hydrodiuril (hydrochlorothiazide), especially for people who are male, 60+ old, also take Lipitor, and have Cystitis noninfective.

The phase IV clinical study analyzes which people have Urinary retention when taking Hydrodiuril. It is created by eHealthMe based on reports of 4,135 people who have side effects when taking Hydrodiuril from the FDA, and is updated regularly.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.

What is Urinary retention?

Urinary retention (the inability to completely or partially empty the bladder) is found to be associated with 1,568 drugs and 1,741 conditions by eHealthMe. Check the latest studies of Urinary retention.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

4,135 people reported to have side effects when taking Hydrodiuril.
Among them, 18 people (0.44%) have Urinary retention.

Could Hydrodiuril cause Urinary retention?

Among these 18 people:

What is the gender of people who have Urinary retention when taking Hydrodiuril? *

female: 41.18 %
male: 58.82 %

What is the age of people who have Urinary retention when taking Hydrodiuril? *

What are other drugs people take besides Hydrodiuril? *

What are other side effects people have besides Urinary retention? *

Headache (pain in head): 4 people, 22.22%
Blood Creatinine Increased: 3 people, 16.67%
Dizziness: 3 people, 16.67%
Muscle Aches (muscle pain): 3 people, 16.67%
Urination - Painful: 3 people, 16.67%
Cough: 3 people, 16.67%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 11.11%
Carotid Bruit (sound heard over the carotid artery area during auscultation): 2 people, 11.11%
Insomnia (sleeplessness): 2 people, 11.11%
Peripheral Sensorimotor Neuropathy (damage to one or more of your peripheral nerves): 2 people, 11.11%

What are the existing conditions these people have? *

Bladder Disorder: 3 people, 16.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 16.67%
Cystitis Noninfective (non-infectious inflammation of the wall of the bladder): 3 people, 16.67%
Enlarged Prostate: 2 people, 11.11%
Quadriplegia (a four limb paralysis): 2 people, 11.11%
Nausea And Vomiting: 2 people, 11.11%
Nausea (feeling of having an urge to vomit): 2 people, 11.11%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 11.11%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.56%
Constipation: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrodiuril and have Urinary retention?

- Check whether Urinary retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrodiuril:

Hydrodiuril (4,211 reports)

Browse all side effects of Hydrodiuril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urinary retention:

Urinary retention (1,568 drugs)

Browse all the conditions that are associated with Urinary retention:

Urinary retention (1,741 conditions)

Related publications that referenced our studies

Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hydrodiuril) and Hydrodiuril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.