Hydroxychloroquine sulfate and Bone marrow failure - a phase IV clinical study of FDA data

Summary:

Bone marrow failure is reported as a side effect among people who take Hydroxychloroquine sulfate (hydroxychloroquine sulfate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Methotrexate, and have Diabetes.

The phase IV clinical study analyzes which people have Bone marrow failure when taking Hydroxychloroquine sulfate. It is created by eHealthMe based on reports of 50,935 people who have side effects when taking Hydroxychloroquine sulfate from the FDA, and is updated regularly.

What is Hydroxychloroquine sulfate?

Hydroxychloroquine sulfate has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. eHealthMe is studying from 52,084 Hydroxychloroquine sulfate users. Check the latest studies of Hydroxychloroquine sulfate.

What is Bone marrow failure?

Bone marrow failure is found to be associated with 1,008 drugs and 1,438 conditions by eHealthMe. Check the latest studies of Bone marrow failure.

On Aug, 08, 2026

50,935 people reported to have side effects when taking Hydroxychloroquine sulfate.
Among them, 15 people (0.03%) have Bone marrow failure.

Could Hydroxychloroquine sulfate cause Bone marrow failure?

Among these 15 people:

How long have people been on Hydroxychloroquine sulfate when they have Bone marrow failure? *

What is the gender of people who have Bone marrow failure when taking Hydroxychloroquine sulfate? *

female: 92.86 %
male: 7.14 %

What is the age of people who have Bone marrow failure when taking Hydroxychloroquine sulfate? *

What are other drugs people take besides Hydroxychloroquine sulfate? *

What are other side effects people have besides Bone marrow failure? *

Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 33.33%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 4 people, 26.67%
Overdose: 3 people, 20.00%
Septic Shock (shock due to blood infection): 3 people, 20.00%
Pneumonia: 2 people, 13.33%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 13.33%
Multi-Organ Failure (multisystem organ failure): 2 people, 13.33%
Febrile Neutropenia (fever with reduced white blood cells): 2 people, 13.33%
Diarrhea: 2 people, 13.33%
Cardiac Failure: 2 people, 13.33%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 3 people, 20.00%
Latent Tuberculosis (hidden tuberculosis): 3 people, 20.00%
High Blood Pressure: 3 people, 20.00%
Diabetes: 3 people, 20.00%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 2 people, 13.33%
Gastric Ulcer (stomach ulcer): 2 people, 13.33%
Pain: 2 people, 13.33%
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 1 person, 6.67%
Haemoglobin Decreased: 1 person, 6.67%
Gastritis (inflammation of stomach): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxychloroquine sulfate and have Bone marrow failure?

- Check whether Bone marrow failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxychloroquine sulfate:

Hydroxychloroquine sulfate (52,084 reports)

Browse all side effects of Hydroxychloroquine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone marrow failure:

Bone marrow failure (1,008 drugs)

Browse all the conditions that are associated with Bone marrow failure:

Bone marrow failure (1,438 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Hydroxychloroquine sulfate) and Hydroxychloroquine sulfate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.