Hydroxychloroquine sulfate and Connective tissue disorder - a phase IV clinical study of FDA data

Summary:

Connective tissue disorder is reported as a side effect among people who take Hydroxychloroquine sulfate (hydroxychloroquine sulfate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Folic Acid, and have Breast cancer.

The phase IV clinical study analyzes which people have Connective tissue disorder when taking Hydroxychloroquine sulfate. It is created by eHealthMe based on reports of 50,935 people who have side effects when taking Hydroxychloroquine sulfate from the FDA, and is updated regularly.

What is Hydroxychloroquine sulfate?

Hydroxychloroquine sulfate has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. eHealthMe is studying from 52,084 Hydroxychloroquine sulfate users. Check the latest studies of Hydroxychloroquine sulfate.

What is Connective tissue disorder?

Connective tissue disorder (any disease that has the connective tissues of the body) is found to be associated with 280 drugs and 389 conditions by eHealthMe. Check the latest studies of Connective tissue disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

50,935 people reported to have side effects when taking Hydroxychloroquine sulfate.
Among them, 24 people (0.05%) have Connective tissue disorder.

Could Hydroxychloroquine sulfate cause Connective tissue disorder?

Among these 24 people:

How long have people been on Hydroxychloroquine sulfate when they have Connective tissue disorder? *

What is the gender of people who have Connective tissue disorder when taking Hydroxychloroquine sulfate? *

female: 100 %
male: 0.0 %

What is the age of people who have Connective tissue disorder when taking Hydroxychloroquine sulfate? *

What are other drugs people take besides Hydroxychloroquine sulfate? *

What are other side effects people have besides Connective tissue disorder? *

Headache (pain in head): 17 people, 70.83%
Joint Pain: 15 people, 62.50%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 12 people, 50.00%
Joint Effusion (presence of extra fluid in joint covering): 12 people, 50.00%
Cataract (clouding of the lens inside the eye): 12 people, 50.00%
Hypersensitivity: 12 people, 50.00%
Pain In Extremity: 12 people, 50.00%
Pain: 11 people, 45.83%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 45.83%
The Flu (the flu is caused by an influenza virus): 11 people, 45.83%

What are the existing conditions these people have? *

Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 25.00%
Joint Pain: 6 people, 25.00%
Breast Cancer: 6 people, 25.00%
Immunodeficiency Common Variable: 5 people, 20.83%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 5 people, 20.83%
Primary Immunodeficiency Syndrome: 4 people, 16.67%
Sinus Disorder (disease of sinus): 1 person, 4.17%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 1 person, 4.17%
Migraine (headache): 1 person, 4.17%
Itching: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxychloroquine sulfate and have Connective tissue disorder?

- Check whether Connective tissue disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxychloroquine sulfate:

Hydroxychloroquine sulfate (52,084 reports)

Browse all side effects of Hydroxychloroquine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Connective tissue disorder:

Connective tissue disorder (280 drugs)

Browse all the conditions that are associated with Connective tissue disorder:

Connective tissue disorder (389 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Hydroxychloroquine sulfate) and Hydroxychloroquine sulfate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.