Hydroxychloroquine sulfate and Papule - a phase IV clinical study of FDA data

Summary:

Papule is reported as a side effect among people who take Hydroxychloroquine sulfate (hydroxychloroquine sulfate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Methotrexate, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Papule when taking Hydroxychloroquine sulfate. It is created by eHealthMe based on reports of 50,935 people who have side effects when taking Hydroxychloroquine sulfate from the FDA, and is updated regularly.

What is Hydroxychloroquine sulfate?

Hydroxychloroquine sulfate has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. eHealthMe is studying from 52,084 Hydroxychloroquine sulfate users. Check the latest studies of Hydroxychloroquine sulfate.

What is Papule?

Papule is found to be associated with 591 drugs and 655 conditions by eHealthMe. Check the latest studies of Papule.



On Jul, 10, 2026

50,935 people reported to have side effects when taking Hydroxychloroquine sulfate.
Among them, 24 people (0.05%) have Papule.

Could Hydroxychloroquine sulfate cause Papule?

Among these 24 people:

How long have people been on Hydroxychloroquine sulfate when they have Papule? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Papule when taking Hydroxychloroquine sulfate? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Papule when taking Hydroxychloroquine sulfate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 42.86 %
  • 50-59: 47.62 %
  • 60+: 9.52 %

What are other drugs people take besides Hydroxychloroquine sulfate? *

  1. Methotrexate: 12 people, 50.00%
  2. Indomethacin: 9 people, 37.50%
  3. Aspirin: 9 people, 37.50%
  4. Dexilant: 8 people, 33.33%
  5. Cosentyx: 8 people, 33.33%
  6. Leflunomide: 7 people, 29.17%
  7. Voltaren: 7 people, 29.17%
  8. Methotrexate Sodium: 5 people, 20.83%
  9. Acetylsalicylic Acid: 2 people, 8.33%
  10. Humira: 2 people, 8.33%

What are other side effects people have besides Papule? *

  1. Rashes (redness): 19 people, 79.17%
  2. Itching: 19 people, 79.17%
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 18 people, 75.00%
  4. Drug Ineffective: 17 people, 70.83%
  5. Pain: 11 people, 45.83%
  6. Joint Pain: 11 people, 45.83%
  7. Feeling Hot: 10 people, 41.67%
  8. Peripheral Swelling: 10 people, 41.67%
  9. Weakness: 10 people, 41.67%
  10. Swelling: 10 people, 41.67%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 37.50%
  2. Muscle Aches (muscle pain): 7 people, 29.17%
  3. Back Pain: 7 people, 29.17%
  4. Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 4.17%
  5. Pain: 1 person, 4.17%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 4.17%
  7. Multiple Myeloma (cancer of the plasma cells): 1 person, 4.17%
  8. Itching: 1 person, 4.17%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 4.17%
  10. Hypersensitivity: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxychloroquine sulfate and have Papule?

- Check whether Papule is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxychloroquine sulfate:

Papule treatments and more:

How severe was Papule and when was it recovered:

Expand to all the drugs that have ingredients of hydroxychloroquine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxychloroquine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Papule:

Browse all the conditions that are associated with Papule:


How the study uses the data?

The study uses data from the FDA. It is based on hydroxychloroquine sulfate (the active ingredients of Hydroxychloroquine sulfate) and Hydroxychloroquine sulfate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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