Hydroxyurea and Blast cell count increased - a phase IV clinical study of FDA data

Summary:

Blast cell count increased is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are male, 60+ old, also take Jakafi, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Blast cell count increased when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Blast cell count increased?

Blast cell count increased is found to be associated with 114 drugs and 181 conditions by eHealthMe. Check the latest studies of Blast cell count increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 31 people (0.18%) have Blast cell count increased.

Could Hydroxyurea cause Blast cell count increased?

Among these 31 people:

What is the gender of people who have Blast cell count increased when taking Hydroxyurea? *

female: 21.74 %
male: 78.26 %

What is the age of people who have Blast cell count increased when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Blast cell count increased? *

White Blood Cell Count Increased: 11 people, 35.48%
Haemoglobin Decreased: 10 people, 32.26%
Thrombocytopenia (decrease of platelets in blood): 10 people, 32.26%
Disease Progression: 8 people, 25.81%
Fever: 7 people, 22.58%
Splenomegaly (enlargement of spleen): 6 people, 19.35%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 16.13%
Anaemia (lack of blood): 5 people, 16.13%
Itching: 4 people, 12.90%
Febrile Neutropenia (fever with reduced white blood cells): 4 people, 12.90%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 10 people, 32.26%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 7 people, 22.58%
Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 19.35%
Haemosiderosis (general increase in tissue iron stores without associated tissue damage): 2 people, 6.45%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 6.45%
Tumor Lysis Syndrome: 1 person, 3.23%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 3.23%
Nausea (feeling of having an urge to vomit): 1 person, 3.23%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 3.23%
Itching: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Blast cell count increased?

- Check whether Blast cell count increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,240 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blast cell count increased:

Blast cell count increased (114 drugs)

Browse all the conditions that are associated with Blast cell count increased:

Blast cell count increased (181 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.