Hydroxyurea and Hypoglycemia - a phase IV clinical study of FDA data

Summary:

Hypoglycemia is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Tylenol, and have High blood pressure.

The phase IV clinical study analyzes which people have Hypoglycemia when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Hypoglycemia?

Hypoglycemia (low blood sugar) is found to be associated with 1,702 drugs and 2,379 conditions by eHealthMe. Check the latest studies of Hypoglycemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 23 people (0.14%) have Hypoglycemia.

Among these 23 people:

How long have people been on Hydroxyurea when they have Hypoglycemia? *

What is the gender of people who have Hypoglycemia when taking Hydroxyurea? *

female: 68.75 %
male: 31.25 %

What is the age of people who have Hypoglycemia when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Hypoglycemia? *

Weakness: 10 people, 43.48%
Hypotension (abnormally low blood pressure): 9 people, 39.13%
Blood Creatinine Increased: 6 people, 26.09%
Nausea (feeling of having an urge to vomit): 6 people, 26.09%
Nausea And Vomiting: 6 people, 26.09%
Bradycardia (abnormally slow heart action): 6 people, 26.09%
Abdominal Pain: 5 people, 21.74%
High Blood Pressure: 5 people, 21.74%
Dehydration (dryness resulting from the removal of water): 5 people, 21.74%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 4 people, 17.39%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 17.39%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 13.04%
Hiv Infection: 3 people, 13.04%
Anaemia (lack of blood): 3 people, 13.04%
Diabetes: 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Neuropathy Peripheral (surface nerve damage): 3 people, 13.04%
Nausea (feeling of having an urge to vomit): 3 people, 13.04%
Urinary Tract Infection: 2 people, 8.70%
Neoplasm Malignant (cancer tumour): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Hypoglycemia?

- Check whether Hypoglycemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,240 reports)

Hypoglycemia treatments and more:

Hypoglycemia (57,734 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoglycemia:

Hypoglycemia (1,702 drugs)

Browse all the conditions that are associated with Hypoglycemia:

Hypoglycemia (2,379 conditions)

Related publications that referenced our studies

Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .
Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.