Hydroxyurea and Ipf - a phase IV clinical study of FDA data

Summary:

Ipf is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Allopurinol, and have Neoplasm malignant.

The phase IV clinical study analyzes which people have Ipf when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,237 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Ipf?

Ipf is found to be associated with 2,140 drugs and 2,253 conditions by eHealthMe. Check the latest studies of Ipf.

On Nov, 16, 2025

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 27 people (0.16%) have Ipf.

Among these 27 people:

How long have people been on Hydroxyurea when they have Ipf? *

What is the gender of people who have Ipf when taking Hydroxyurea? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Ipf when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Ipf? *

Pneumonia: 8 people, 29.63%
Interstitial Lung Disease: 7 people, 25.93%
Intestinal Obstruction: 5 people, 18.52%
Haemoglobin Decreased: 5 people, 18.52%
Pleural Effusion (water on the lungs): 4 people, 14.81%
Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 14.81%
Unilateral Hydronephrosis (kidney stone that causes obstruction of the ureter): 4 people, 14.81%
Blood Lactate Dehydrogenase Increased: 4 people, 14.81%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 14.81%
Depression: 4 people, 14.81%

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 4 people, 14.81%
Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 11.11%
Pneumonia: 3 people, 11.11%
Fever: 3 people, 11.11%
Essential Thrombocythaemia (chronic blood cancer): 3 people, 11.11%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 11.11%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Ipf?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,237 reports)

Ipf treatments and more:

Ipf (79,192 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ipf:

Ipf (2,140 drugs)

Browse all the conditions that are associated with Ipf:

Ipf (2,253 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.