Hydroxyurea and Nail pigmentation - a phase IV clinical study of FDA data

Summary:

Nail pigmentation is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are female, 60+ old, also take Fish Oil, and have Chronic myeloid leukaemia.

The phase IV clinical study analyzes which people have Nail pigmentation when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Nail pigmentation?

Nail pigmentation (nail colour) is found to be associated with 21 drugs and 187 conditions by eHealthMe. Check the latest studies of Nail pigmentation.

On Jul, 05, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 20 people (0.12%) have Nail pigmentation.

Could Hydroxyurea cause Nail pigmentation?

Among these 20 people:

What is the gender of people who have Nail pigmentation when taking Hydroxyurea? *

female: 80 %
male: 20 %

What is the age of people who have Nail pigmentation when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Nail pigmentation? *

Skin Hyperpigmentation (disorders affect the colour of your skin): 8 people, 40.00%
Skin Ulcer: 6 people, 30.00%
Skin Atrophy (wasting of skin): 5 people, 25.00%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 4 people, 20.00%
Ichthyosis Acquired (acquired skin disorders): 3 people, 15.00%
Fever: 3 people, 15.00%
Dry Skin: 2 people, 10.00%
Pigmentation Disorder (disturbances of human skin colour): 2 people, 10.00%
Actinic Keratosis (skin disease due to sun exposure): 2 people, 10.00%
Tongue Pigmentation (colouring of tongue): 2 people, 10.00%

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 20.00%
Essential Thrombocythaemia (chronic blood cancer): 2 people, 10.00%
Thrombocytosis: 1 person, 5.00%
Skin Cancer: 1 person, 5.00%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 5.00%
Haematological Malignancy (cancer that affect blood, bone marrow, and lymph nodes): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Nail pigmentation?

- Check whether Nail pigmentation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,240 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nail pigmentation:

Nail pigmentation (21 drugs)

Browse all the conditions that are associated with Nail pigmentation:

Nail pigmentation (187 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.