Hydroxyurea and Purpura - a phase IV clinical study of FDA data

Summary:

Purpura is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Cytarabine, and have Acute leukaemia.

The phase IV clinical study analyzes which people have Purpura when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Purpura?

Purpura (purplish discoloration of the skin) is found to be associated with 941 drugs and 1,515 conditions by eHealthMe. Check the latest studies of Purpura.

On Jul, 11, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 16 people (0.09%) have Purpura.

Among these 16 people:

How long have people been on Hydroxyurea when they have Purpura? *

What is the gender of people who have Purpura when taking Hydroxyurea? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Purpura when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

Cytarabine: 9 people, 56.25%
Acetaminophen: 7 people, 43.75%
Benzonatate: 7 people, 43.75%
Chlorhexidine Gluconate: 7 people, 43.75%
Melatonin: 7 people, 43.75%
Methotrexate: 7 people, 43.75%
Oxycodone: 7 people, 43.75%
Potassium: 6 people, 37.50%
Magnesium: 6 people, 37.50%
Posaconazole: 4 people, 25.00%

What are other side effects people have besides Purpura? *

Angiokeratoma (a skin disease in which warty growths occur in groups, together with epidermal thickening): 8 people, 50.00%
Palmar Erythema (reddening of the palms at the thenar and hypothenar eminences): 7 people, 43.75%
Dyspnea (difficult or laboured breathing): 5 people, 31.25%
Haemorrhage (bleeding): 5 people, 31.25%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 18.75%
Nausea (feeling of having an urge to vomit): 3 people, 18.75%
Asthma: 3 people, 18.75%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 3 people, 18.75%
Fainting (loss of consciousness and postural tone): 3 people, 18.75%
Fatigue (feeling of tiredness): 3 people, 18.75%

What are the existing conditions these people have? *

Acute Leukaemia (blood cancer): 7 people, 43.75%
Oedema Peripheral (superficial swelling): 3 people, 18.75%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 18.75%
Asthma: 3 people, 18.75%
Splenomegaly (enlargement of spleen): 1 person, 6.25%
Leukaemia (blood or bone marrow cancer): 1 person, 6.25%
Essential Thrombocythaemia (chronic blood cancer): 1 person, 6.25%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Purpura?

- Check whether Purpura is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,240 reports)

Purpura treatments and more:

Purpura (10,762 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Purpura:

Purpura (941 drugs)

Browse all the conditions that are associated with Purpura:

Purpura (1,515 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.