Hydroxyurea and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are male, 50-59 old, have been taking the drug for 5 - 10 years also take Atenolol, and have Diabetes.

The phase IV clinical study analyzes which people have Shock when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,234 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,354 drugs and 1,748 conditions by eHealthMe. Check the latest studies of Shock.



On Sep, 11, 2025

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 13 people (0.08%) have Shock.

Could Hydroxyurea cause Shock?

Among these 13 people:

How long have people been on Hydroxyurea when they have Shock? *

  • < 1 month: 14.29 %
  • 1 - 6 months: 14.29 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 71.43 %
  • 10+ years: 0.0 %

What is the gender of people who have Shock when taking Hydroxyurea? *

  • female: 8.33 %
  • male: 91.67 %

What is the age of people who have Shock when taking Hydroxyurea? *

  • 0-1: 0.0 %
  • 2-9: 8.33 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 50.0 %
  • 60+: 25.0 %

What are other drugs people take besides Hydroxyurea? *

  1. Gliclazide: 5 people, 38.46%
  2. Atenolol: 5 people, 38.46%
  3. Aspirin: 4 people, 30.77%
  4. Vitamin D: 2 people, 15.38%
  5. Anagrelide Hydrochloride: 2 people, 15.38%
  6. Zosyn: 1 person, 7.69%
  7. Creon: 1 person, 7.69%
  8. Foradil: 1 person, 7.69%
  9. Flagyl: 1 person, 7.69%
  10. Dipyrone: 1 person, 7.69%

What are other side effects people have besides Shock? *

  1. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 5 people, 38.46%
  2. Arrhythmias (irregular heartbeat): 5 people, 38.46%
  3. Hypotension (abnormally low blood pressure): 4 people, 30.77%
  4. Torsade De Pointes (a abnormal heart rate with abnormal beating pattern): 4 people, 30.77%
  5. Dizziness: 4 people, 30.77%
  6. Respiratory Depression (respiration has a rate below 12 breaths): 4 people, 30.77%
  7. Heart Attack: 3 people, 23.08%
  8. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 23.08%
  9. Loss Of Consciousness: 3 people, 23.08%
  10. Mydriasis (a dilation of the pupil): 3 people, 23.08%

What are the existing conditions these people have? *

  1. High Blood Pressure: 5 people, 38.46%
  2. Diabetes: 5 people, 38.46%
  3. Enlarged Prostate: 3 people, 23.08%
  4. Essential Thrombocythaemia (chronic blood cancer): 3 people, 23.08%
  5. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 15.38%
  6. Prostatic Disorder: 2 people, 15.38%
  7. Depression: 2 people, 15.38%
  8. Anaemia (lack of blood): 1 person, 7.69%
  9. Bone Marrow Conditioning Regimen: 1 person, 7.69%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Shock?

- Check whether Shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Shock treatments and more:

How severe was Shock and when was it recovered:

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shock:

Browse all the conditions that are associated with Shock:

  • Shock (1,748 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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