Hydroxyurea and Sleeping difficulty - a phase IV clinical study of FDA data
Summary:
Sleeping difficulty is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Jakafi, and have Primary myelofibrosis.
The phase IV clinical study analyzes which people have Sleeping difficulty when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.
What is Hydroxyurea?
Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,235 Hydroxyurea users. Check the latest studies of Hydroxyurea.
What is Sleeping difficulty?
Sleeping difficulty (difficult sleeping) is found to be associated with 4,244 drugs and 5,347 conditions by eHealthMe. Check the latest studies of Sleeping difficulty.
16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 305 people (1.8%) have Sleeping difficulty.

Among these 305 people:
How long have people been on Hydroxyurea when they have Sleeping difficulty? *
- < 1 month: 56.25 %
- 1 - 6 months: 37.5 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 6.25 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Sleeping difficulty when taking Hydroxyurea? *
- female: 45.66 %
- male: 54.34 %
What is the age of people who have Sleeping difficulty when taking Hydroxyurea? *
- 0-1: 0.0 %
- 2-9: 0.75 %
- 10-19: 24.06 %
- 20-29: 0.75 %
- 30-39: 4.51 %
- 40-49: 6.77 %
- 50-59: 15.79 %
- 60+: 47.37 %
What are other drugs people take besides Hydroxyurea? *
- Jakafi: 129 people, 42.30%
- Vitamin D3: 43 people, 14.10%
- Aspirin: 37 people, 12.13%
- Clopidogrel: 30 people, 9.84%
- Hydrocodone: 28 people, 9.18%
- Vitamin C: 28 people, 9.18%
- Xarelto: 27 people, 8.85%
- Besremi: 27 people, 8.85%
- Klonopin: 26 people, 8.52%
- Vitamin D2: 26 people, 8.52%
What are other side effects people have besides Sleeping difficulty? *
- Fatigue (feeling of tiredness): 165 people, 54.10%
- Diarrhea: 116 people, 38.03%
- Stress And Anxiety: 106 people, 34.75%
- Nausea (feeling of having an urge to vomit): 93 people, 30.49%
- Weakness: 79 people, 25.90%
- Dizziness: 78 people, 25.57%
- Depression: 77 people, 25.25%
- Headache (pain in head): 77 people, 25.25%
- Weight Decreased: 76 people, 24.92%
- Platelet Count Increased: 74 people, 24.26%
What are the existing conditions these people have? *
- Primary Myelofibrosis (primary disorder of the bone marrow): 45 people, 14.75%
- Depression: 24 people, 7.87%
- Pain: 22 people, 7.21%
- Stress And Anxiety: 16 people, 5.25%
- Tooth Fracture: 15 people, 4.92%
- Bone Pain: 15 people, 4.92%
- Joint Pain: 11 people, 3.61%
- Essential Thrombocythaemia (chronic blood cancer): 10 people, 3.28%
- Urinary Tract Infection: 9 people, 2.95%
- Constipation: 8 people, 2.62%
* Approximation only. Some reports may have incomplete information.
Do you take Hydroxyurea and have Sleeping difficulty?
- Check whether Sleeping difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:
- Hydroxyurea (17,235 reports)
Sleeping difficulty treatments and more:
- Sleeping difficulty (437,973 reports)
How severe was Sleeping difficulty and when was it recovered:
Expand to all the drugs that have ingredients of hydroxyurea:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Hydroxyurea side effects:
- Hydroxyurea side effect: Headache (pain in head) (1,230 reports)
- Hydroxyurea side effect: Thrombocytopenia (decrease of platelets in blood) (1,079 reports)
- Hydroxyurea side effect: Haemoglobin decreased (988 reports)
- Hydroxyurea side effect: Pain (974 reports)
- Hydroxyurea side effect: Anaemia (lack of blood) (935 reports)
Browse all side effects of Hydroxyurea:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Sleeping difficulty:
- Prednisone side effect: Sleeping difficulty (14,705 reports)
- Aspirin side effect: Sleeping difficulty (12,925 reports)
- Lyrica side effect: Sleeping difficulty (11,256 reports)
- Cymbalta side effect: Sleeping difficulty (10,012 reports)
- Methotrexate side effect: Sleeping difficulty (9,775 reports)
- Humira side effect: Sleeping difficulty (9,315 reports)
- Vitamin d side effect: Sleeping difficulty (8,911 reports)
- Gabapentin side effect: Sleeping difficulty (8,794 reports)
- Omeprazole side effect: Sleeping difficulty (8,666 reports)
- Synthroid side effect: Sleeping difficulty (8,339 reports)
Browse all the drugs that are associated with Sleeping difficulty:
- Sleeping difficulty (4,244 drugs)
Common conditions associated with Sleeping difficulty:
- Depression aggravated: 17,540 reports
- Antidepressant therapy: 17,500 reports
- Pain exacerbated: 13,668 reports
- Rheumatoid arthritis aggravated: 13,625 reports
- Alternative medicine - pain relief: 13,485 reports
- Multiple sclerosis: 12,998 reports
- Hypertension aggravated: 12,107 reports
- Blood pressure increased: 12,061 reports
- Anxiety: 10,449 reports
- Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 10,431 reports
Browse all the conditions that are associated with Sleeping difficulty:
- Sleeping difficulty (5,347 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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