Hydroxyurea and Staphylococcal infection - a phase IV clinical study of FDA data

Summary:

Staphylococcal infection is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Septic shock.

The phase IV clinical study analyzes which people have Staphylococcal infection when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Staphylococcal infection?

Staphylococcal infection (an infection with staphylococcus bacteria) is found to be associated with 1,724 drugs and 1,898 conditions by eHealthMe. Check the latest studies of Staphylococcal infection.

On Jul, 11, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 68 people (0.4%) have Staphylococcal infection.

Could Hydroxyurea cause Staphylococcal infection?

Among these 68 people:

How long have people been on Hydroxyurea when they have Staphylococcal infection? *

What is the gender of people who have Staphylococcal infection when taking Hydroxyurea? *

female: 33.96 %
male: 66.04 %

What is the age of people who have Staphylococcal infection when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Staphylococcal infection? *

Pneumonia: 16 people, 23.53%
Fever: 12 people, 17.65%
Respiratory Distress (difficulty in breathing): 8 people, 11.76%
Anaemia (lack of blood): 8 people, 11.76%
Pain: 8 people, 11.76%
Hypokalemia (low potassium): 7 people, 10.29%
Hypotension (abnormally low blood pressure): 7 people, 10.29%
Skin Ulcer: 7 people, 10.29%
Thrombocytopenia (decrease of platelets in blood): 6 people, 8.82%
Diarrhea: 6 people, 8.82%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 10.29%
Septic Shock (shock due to blood infection): 7 people, 10.29%
Iron Overload: 6 people, 8.82%
Bone Marrow Conditioning Regimen: 5 people, 7.35%
High Blood Pressure: 4 people, 5.88%
Polycythaemia (proportion of blood volume that is occupied by red blood cells increases): 3 people, 4.41%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 4.41%
Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 2.94%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 2.94%
Gastroenteritis Staphylococcal (inflammation of stomach and intestine caused by staphylococcal infection): 1 person, 1.47%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Staphylococcal infection?

- Check whether Staphylococcal infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,240 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Staphylococcal infection:

Staphylococcal infection (1,724 drugs)

Browse all the conditions that are associated with Staphylococcal infection:

Staphylococcal infection (1,898 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.