Hydroxyzine hydrochloride and Concussion - a phase IV clinical study of FDA data

Summary:

Concussion is reported as a side effect among people who take Hydroxyzine hydrochloride (hydroxyzine hydrochloride), especially for people who are female, 40-49 old, also take Metformin Hydrochloride, and have Cataplexy.

The phase IV clinical study analyzes which people have Concussion when taking Hydroxyzine hydrochloride. It is created by eHealthMe based on reports of 10,079 people who have side effects when taking Hydroxyzine hydrochloride from the FDA, and is updated regularly.

What is Hydroxyzine hydrochloride?

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 10,486 Hydroxyzine hydrochloride users. Check the latest studies of Hydroxyzine hydrochloride.

What is Concussion?

Concussion (short loss of normal brain function in response to a head injury) is found to be associated with 771 drugs and 780 conditions by eHealthMe. Check the latest studies of Concussion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 21, 2026

10,079 people reported to have side effects when taking Hydroxyzine hydrochloride.
Among them, 12 people (0.12%) have Concussion.

Could Hydroxyzine hydrochloride cause Concussion?

Among these 12 people:

What is the gender of people who have Concussion when taking Hydroxyzine hydrochloride? *

  • female: 83.33 %
  • male: 16.67 %

What is the age of people who have Concussion when taking Hydroxyzine hydrochloride? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 55.56 %
  • 50-59: 22.22 %
  • 60+: 22.22 %

What are other drugs people take besides Hydroxyzine hydrochloride? *

  1. Lidocaine: 3 people, 25.00%
  2. Levothyroxine Sodium: 3 people, 25.00%
  3. Dupixent: 3 people, 25.00%
  4. Ibuprofen: 3 people, 25.00%
  5. Baclofen: 3 people, 25.00%
  6. Metformin Hydrochloride: 3 people, 25.00%
  7. Lansoprazole: 2 people, 16.67%
  8. Cyanocobalamin: 2 people, 16.67%
  9. Clonazepam: 2 people, 16.67%
  10. Lisinopril: 2 people, 16.67%

What are other side effects people have besides Concussion? *

  1. Fall: 6 people, 50.00%
  2. Headache (pain in head): 6 people, 50.00%
  3. Head Injury: 4 people, 33.33%
  4. Loss Of Consciousness: 4 people, 33.33%
  5. Road Traffic Accident: 4 people, 33.33%
  6. Dizziness: 4 people, 33.33%
  7. Pain: 3 people, 25.00%
  8. Memory Loss: 3 people, 25.00%
  9. Hypoaesthesia (reduced sense of touch or sensation): 3 people, 25.00%
  10. Sedation: 2 people, 16.67%

What are the existing conditions these people have? *

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 16.67%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 16.67%
  3. Drowsiness: 2 people, 16.67%
  4. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 16.67%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 16.67%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 8.33%
  7. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 8.33%
  8. Nasal Polyps (masses that develop in the lining of the nose): 1 person, 8.33%
  9. Folliculitis (infection of hair root): 1 person, 8.33%
  10. Cystic Fibrosis (disease of the secretary glands): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine hydrochloride and have Concussion?

- Check whether Concussion is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine hydrochloride:

Concussion treatments and more:

How severe was Concussion and when was it recovered:

Expand to all the drugs that have ingredients of hydroxyzine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyzine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Concussion:

Browse all the conditions that are associated with Concussion:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine hydrochloride) and Hydroxyzine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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