Hydroxyzine hydrochloride and Fibromyalgia - a phase IV clinical study of FDA data

Summary:

Fibromyalgia is reported as a side effect among people who take Hydroxyzine hydrochloride (hydroxyzine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Prednisone, and have Narcolepsy.

The phase IV clinical study analyzes which people have Fibromyalgia when taking Hydroxyzine hydrochloride. It is created by eHealthMe based on reports of 10,079 people who have side effects when taking Hydroxyzine hydrochloride from the FDA, and is updated regularly.

What is Hydroxyzine hydrochloride?

Hydroxyzine hydrochloride has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 10,486 Hydroxyzine hydrochloride users. Check the latest studies of Hydroxyzine hydrochloride.

What is Fibromyalgia?

Fibromyalgia (a long-term condition which causes pain all over the body) is found to be associated with 1,337 drugs and 1,834 conditions by eHealthMe. Check the latest studies of Fibromyalgia.

On Jul, 26, 2026

10,079 people reported to have side effects when taking Hydroxyzine hydrochloride.
Among them, 30 people (0.3%) have Fibromyalgia.

Could Hydroxyzine hydrochloride cause Fibromyalgia?

Among these 30 people:

How long have people been on Hydroxyzine hydrochloride when they have Fibromyalgia? *

What is the gender of people who have Fibromyalgia when taking Hydroxyzine hydrochloride? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Fibromyalgia when taking Hydroxyzine hydrochloride? *

What are other drugs people take besides Hydroxyzine hydrochloride? *

What are other side effects people have besides Fibromyalgia? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 33.33%
Pain: 10 people, 33.33%
Fatigue (feeling of tiredness): 8 people, 26.67%
Asthma: 8 people, 26.67%
Abdominal Pain Upper: 6 people, 20.00%
Stable Angina (a constant chest pain): 6 people, 20.00%
Nausea And Vomiting: 5 people, 16.67%
The Flu (the flu is caused by an influenza virus): 5 people, 16.67%
Weight Decreased: 5 people, 16.67%
Nerve Compression: 5 people, 16.67%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 20.00%
Pain: 6 people, 20.00%
Asthma: 5 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 16.67%
Immunodeficiency Common Variable: 4 people, 13.33%
High Blood Pressure: 4 people, 13.33%
Drowsiness: 4 people, 13.33%
Hypersensitivity: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine hydrochloride and have Fibromyalgia?

- Check whether Fibromyalgia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine hydrochloride:

Hydroxyzine hydrochloride (10,486 reports)

Fibromyalgia treatments and more:

Fibromyalgia (92,987 reports)

Browse all side effects of Hydroxyzine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fibromyalgia:

Fibromyalgia (1,337 drugs)

Browse all the conditions that are associated with Fibromyalgia:

Fibromyalgia (1,834 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine hydrochloride) and Hydroxyzine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.