Hydroxyzine and Depression suicidal - a phase IV clinical study of FDA data

Summary:

Depression suicidal is reported as a side effect among people who take Hydroxyzine (hydroxyzine hydrochloride), especially for people who are male, 20-29 old, have been taking the drug for 2 - 5 years also take Sertraline, and have Depression.

The phase IV clinical study analyzes which people have Depression suicidal when taking Hydroxyzine. It is created by eHealthMe based on reports of 51,890 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,070 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Depression suicidal?

Depression suicidal (suicide depressive disorder) is found to be associated with 314 drugs and 474 conditions by eHealthMe. Check the latest studies of Depression suicidal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

51,890 people reported to have side effects when taking Hydroxyzine.
Among them, 13 people (0.03%) have Depression suicidal.

Could Hydroxyzine cause Depression suicidal?

Among these 13 people:

How long have people been on Hydroxyzine when they have Depression suicidal? *

What is the gender of people who have Depression suicidal when taking Hydroxyzine? *

female: 15.38 %
male: 84.62 %

What is the age of people who have Depression suicidal when taking Hydroxyzine? *

What are other drugs people take besides Hydroxyzine? *

What are other side effects people have besides Depression suicidal? *

Crying: 8 people, 61.54%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 6 people, 46.15%
Chronic Kidney Disease: 6 people, 46.15%
Emotional Distress: 6 people, 46.15%
Pain: 6 people, 46.15%
Osteoporosis (bones weak and more likely to break): 6 people, 46.15%
Acute Kidney Failure: 5 people, 38.46%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 38.46%
Upper Limb Fracture: 4 people, 30.77%
Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 4 people, 30.77%

What are the existing conditions these people have? *

Depression: 7 people, 53.85%
Hypersensitivity: 6 people, 46.15%
Pain: 6 people, 46.15%
Hiv Infection: 6 people, 46.15%
Eye Irritation: 4 people, 30.77%
High Blood Pressure: 4 people, 30.77%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 30.77%
Gingivitis (inflammation of gums): 4 people, 30.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 30.77%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 30.77%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Depression suicidal?

- Check whether Depression suicidal is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine:

Hydroxyzine (54,070 reports)

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression suicidal:

Depression suicidal (314 drugs)

Browse all the conditions that are associated with Depression suicidal:

Depression suicidal (474 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.