Hydroxyzine and Flank pain - a phase IV clinical study of FDA data

Summary:

Flank pain is reported as a side effect among people who take Hydroxyzine (hydroxyzine hydrochloride), especially for people who are female, 60+ old, also take Neurontin, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Flank pain when taking Hydroxyzine. It is created by eHealthMe based on reports of 51,890 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Flank pain?

Flank pain (a distressing sensation experienced around the lower back and the upper abdomen) is found to be associated with 1,133 drugs and 1,476 conditions by eHealthMe. Check the latest studies of Flank pain.

On May, 02, 2026

51,890 people reported to have side effects when taking Hydroxyzine.
Among them, 49 people (0.09%) have Flank pain.

Among these 49 people:

What is the gender of people who have Flank pain when taking Hydroxyzine? *

female: 81.63 %
male: 18.37 %

What is the age of people who have Flank pain when taking Hydroxyzine? *

What are other drugs people take besides Hydroxyzine? *

What are other side effects people have besides Flank pain? *

Pain: 22 people, 44.90%
Back Pain: 18 people, 36.73%
Chest Pain: 18 people, 36.73%
Abdominal Pain: 17 people, 34.69%
Depression: 16 people, 32.65%
Joint Pain: 16 people, 32.65%
Emotional Distress: 15 people, 30.61%
Nausea (feeling of having an urge to vomit): 15 people, 30.61%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 14 people, 28.57%
Haematochezia (passage of stools containing blood): 14 people, 28.57%

What are the existing conditions these people have? *

Depression: 10 people, 20.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 20.41%
Nausea (feeling of having an urge to vomit): 9 people, 18.37%
Pain: 9 people, 18.37%
High Blood Pressure: 9 people, 18.37%
Osteoporosis (bones weak and more likely to break): 7 people, 14.29%
Neoplasm Malignant (cancer tumour): 7 people, 14.29%
Muscle Spasms (muscle contraction): 5 people, 10.20%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 10.20%
Asthma: 5 people, 10.20%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Flank pain?

- Check whether Flank pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine:

Hydroxyzine (54,069 reports)

Flank pain treatments and more:

Flank pain (12,893 reports)

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flank pain:

Flank pain (1,133 drugs)

Browse all the conditions that are associated with Flank pain:

Flank pain (1,476 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.