Hydroxyzine and Haemodynamic instability - a phase IV clinical study of FDA data

Summary:

Haemodynamic instability is reported as a side effect among people who take Hydroxyzine (hydroxyzine hydrochloride), especially for people who are male, 60+ old, also take Fluconazole, and have Schizophrenia.

The phase IV clinical study analyzes which people have Haemodynamic instability when taking Hydroxyzine. It is created by eHealthMe based on reports of 51,890 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Haemodynamic instability?

Haemodynamic instability (disturbances in the blood movement in our body) is found to be associated with 552 drugs and 1,279 conditions by eHealthMe. Check the latest studies of Haemodynamic instability.

On Jul, 06, 2026

51,890 people reported to have side effects when taking Hydroxyzine.
Among them, 46 people (0.09%) have Haemodynamic instability.

Could Hydroxyzine cause Haemodynamic instability?

Among these 46 people:

What is the gender of people who have Haemodynamic instability when taking Hydroxyzine? *

female: 50 %
male: 50 %

What is the age of people who have Haemodynamic instability when taking Hydroxyzine? *

What are other drugs people take besides Hydroxyzine? *

What are other side effects people have besides Haemodynamic instability? *

Hypotension (abnormally low blood pressure): 20 people, 43.48%
Fever: 19 people, 41.30%
Acute Kidney Failure: 18 people, 39.13%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 17 people, 36.96%
Septic Shock (shock due to blood infection): 12 people, 26.09%
Tachypnea: 11 people, 23.91%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 9 people, 19.57%
Lactic Acidosis (low ph in body tissues): 9 people, 19.57%
Nausea (feeling of having an urge to vomit): 9 people, 19.57%
Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 9 people, 19.57%

What are the existing conditions these people have? *

Pain: 4 people, 8.70%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 8.70%
Neck Pain: 2 people, 4.35%
Drug Dependence: 2 people, 4.35%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 4.35%
Neuralgia (pain in one or more nerves): 2 people, 4.35%
Back Pain: 2 people, 4.35%
Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 4.35%
Oedema (fluid collection in tissue): 1 person, 2.17%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Haemodynamic instability?

- Check whether Haemodynamic instability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine:

Hydroxyzine (54,069 reports)

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemodynamic instability:

Haemodynamic instability (552 drugs)

Browse all the conditions that are associated with Haemodynamic instability:

Haemodynamic instability (1,279 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.