Hydroxyzine and Hypophosphataemia - a phase IV clinical study of FDA data

Summary:

Hypophosphataemia is reported as a side effect among people who take Hydroxyzine (hydroxyzine hydrochloride), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Unituxin, and have Iron deficiency anaemia.

The phase IV clinical study analyzes which people have Hypophosphataemia when taking Hydroxyzine. It is created by eHealthMe based on reports of 51,890 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Hypophosphataemia?

Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood) is found to be associated with 872 drugs and 781 conditions by eHealthMe. Check the latest studies of Hypophosphataemia.

On Jul, 18, 2026

51,890 people reported to have side effects when taking Hydroxyzine.
Among them, 41 people (0.08%) have Hypophosphataemia.

Could Hydroxyzine cause Hypophosphataemia?

Among these 41 people:

How long have people been on Hydroxyzine when they have Hypophosphataemia? *

What is the gender of people who have Hypophosphataemia when taking Hydroxyzine? *

female: 65.85 %
male: 34.15 %

What is the age of people who have Hypophosphataemia when taking Hydroxyzine? *

What are other drugs people take besides Hydroxyzine? *

What are other side effects people have besides Hypophosphataemia? *

Pain: 18 people, 43.90%
Fever: 12 people, 29.27%
Hypokalemia (low potassium): 12 people, 29.27%
Abdominal Pain: 11 people, 26.83%
Anaemia (lack of blood): 11 people, 26.83%
Thrombocytopenia (decrease of platelets in blood): 11 people, 26.83%
Malaise (a feeling of general discomfort or uneasiness): 11 people, 26.83%
Pain In Extremity: 10 people, 24.39%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 10 people, 24.39%
Aspartate Aminotransferase Increased: 9 people, 21.95%

What are the existing conditions these people have? *

Iron Deficiency Anaemia: 14 people, 34.15%
Pain: 11 people, 26.83%
Neuroblastoma (a cancer that forms in your nerve tissue): 8 people, 19.51%
Multiple Myeloma (cancer of the plasma cells): 5 people, 12.20%
Vena Cava Thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart): 5 people, 12.20%
Pancreatic Carcinoma (pancreatic cancer): 5 people, 12.20%
Thrombosis (formation of a blood clot inside a blood vessel): 5 people, 12.20%
Diabetes: 4 people, 9.76%
Vitamin B12 Deficiency: 4 people, 9.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.76%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Hypophosphataemia?

- Check whether Hypophosphataemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine:

Hydroxyzine (54,069 reports)

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypophosphataemia:

Hypophosphataemia (872 drugs)

Browse all the conditions that are associated with Hypophosphataemia:

Hypophosphataemia (781 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.