Hydroxyzine and Psychotic disorder - a phase IV clinical study of FDA data

Summary:

Psychotic disorder is reported as a side effect among people who take Hydroxyzine (hydroxyzine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Lyrica, and have Pain.

The phase IV clinical study analyzes which people have Psychotic disorder when taking Hydroxyzine. It is created by eHealthMe based on reports of 51,890 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,069 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Psychotic disorder?

Psychotic disorder is found to be associated with 1,230 drugs and 1,472 conditions by eHealthMe. Check the latest studies of Psychotic disorder.

On Jul, 27, 2026

51,890 people reported to have side effects when taking Hydroxyzine.
Among them, 136 people (0.26%) have Psychotic disorder.

Could Hydroxyzine cause Psychotic disorder?

Among these 136 people:

How long have people been on Hydroxyzine when they have Psychotic disorder? *

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What is the gender of people who have Psychotic disorder when taking Hydroxyzine? *

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What is the age of people who have Psychotic disorder when taking Hydroxyzine? *

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* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Psychotic disorder?

- Check whether Psychotic disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine:

Hydroxyzine (54,069 reports)

Psychotic disorder treatments and more:

Psychotic disorder (61,342 reports)

How severe was Psychotic disorder and when was it recovered:

Psychotic disorder in Hydroxyzine

Expand to all the drugs that have ingredients of hydroxyzine hydrochloride:

Psychotic disorder and drugs with ingredients of hydroxyzine hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psychotic disorder:

Psychotic disorder (1,230 drugs)

Browse all the conditions that are associated with Psychotic disorder:

Psychotic disorder (1,472 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.