Hyzaar and Blood urea increased - a phase IV clinical study of FDA data

Summary:

Blood urea increased is reported as a side effect among people who take Hyzaar (hydrochlorothiazide; losartan potassium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lasix, and have Osteoporosis.

The phase IV clinical study analyzes which people have Blood urea increased when taking Hyzaar. It is created by eHealthMe based on reports of 15,960 people who have side effects when taking Hyzaar from the FDA, and is updated regularly.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.

What is Blood urea increased?

Blood urea increased is found to be associated with 1,622 drugs and 1,990 conditions by eHealthMe. Check the latest studies of Blood urea increased.

On Jul, 13, 2026

15,960 people reported to have side effects when taking Hyzaar.
Among them, 95 people (0.6%) have Blood urea increased.

Could Hyzaar cause Blood urea increased?

Among these 95 people:

How long have people been on Hyzaar when they have Blood urea increased? *

What is the gender of people who have Blood urea increased when taking Hyzaar? *

female: 50.54 %
male: 49.46 %

What is the age of people who have Blood urea increased when taking Hyzaar? *

What are other drugs people take besides Hyzaar? *

What are other side effects people have besides Blood urea increased? *

Blood Creatinine Increased: 76 people, 80.00%
Haematocrit Decreased: 26 people, 27.37%
Haemoglobin Decreased: 25 people, 26.32%
Fatigue (feeling of tiredness): 24 people, 25.26%
Pain: 20 people, 21.05%
Red Blood Cell Count Decreased: 19 people, 20.00%
Constipation: 19 people, 20.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 18 people, 18.95%
Blood Alkaline Phosphatase Increased: 17 people, 17.89%
Nausea (feeling of having an urge to vomit): 16 people, 16.84%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 6 people, 6.32%
Depression: 5 people, 5.26%
Muscle Spasms (muscle contraction): 3 people, 3.16%
Hepatitis C: 3 people, 3.16%
Asthma: 3 people, 3.16%
High Blood Cholesterol: 3 people, 3.16%
Pain: 3 people, 3.16%
Metastases To Bone (cancer spreads to bone): 3 people, 3.16%
Multiple Myeloma (cancer of the plasma cells): 2 people, 2.11%
Essential Hypertension (primary hypertension): 2 people, 2.11%

* Approximation only. Some reports may have incomplete information.

Do you take Hyzaar and have Blood urea increased?

- Check whether Blood urea increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hyzaar:

Hyzaar (16,614 reports)

Blood urea increased treatments and more:

Blood urea increased (29,976 reports)

How severe was Blood urea increased and when was it recovered:

Blood urea increased in Hyzaar

Expand to all the drugs that have ingredients of hydrochlorothiazide; losartan potassium:

Blood urea increased and drugs with ingredients of hydrochlorothiazide; losartan potassium

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hyzaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood urea increased:

Blood urea increased (1,622 drugs)

Browse all the conditions that are associated with Blood urea increased:

Blood urea increased (1,990 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; losartan potassium (the active ingredients of Hyzaar) and Hyzaar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.