Hyzaar and Hypophosphataemia - a phase IV clinical study of FDA data

Summary:

Hypophosphataemia is reported as a side effect among people who take Hyzaar (hydrochlorothiazide; losartan potassium), especially for people who are female, 60+ old, also take Xanax, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Hypophosphataemia when taking Hyzaar. It is created by eHealthMe based on reports of 15,960 people who have side effects when taking Hyzaar from the FDA, and is updated regularly.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.

What is Hypophosphataemia?

Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood) is found to be associated with 869 drugs and 781 conditions by eHealthMe. Check the latest studies of Hypophosphataemia.

On Aug, 08, 2026

15,960 people reported to have side effects when taking Hyzaar.
Among them, 15 people (0.09%) have Hypophosphataemia.

Among these 15 people:

What is the gender of people who have Hypophosphataemia when taking Hyzaar? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Hypophosphataemia when taking Hyzaar? *

What are other drugs people take besides Hyzaar? *

What are other side effects people have besides Hypophosphataemia? *

Hypokalemia (low potassium): 13 people, 86.67%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 8 people, 53.33%
Death: 5 people, 33.33%
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 3 people, 20.00%
Stress And Anxiety: 3 people, 20.00%
Pneumonia: 3 people, 20.00%
Peripheral Vascular Disorder: 3 people, 20.00%
Fistula (an abnormal connection or passageway between two): 3 people, 20.00%
Diarrhea: 3 people, 20.00%
Pain: 3 people, 20.00%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 8 people, 53.33%
Stress And Anxiety: 2 people, 13.33%
Multiple Myeloma (cancer of the plasma cells): 2 people, 13.33%
Insomnia (sleeplessness): 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 6.67%
Hiv Infection: 1 person, 6.67%
Erythema Nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below): 1 person, 6.67%
Breast Cancer: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hyzaar and have Hypophosphataemia?

- Check whether Hypophosphataemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hyzaar:

Hyzaar (16,614 reports)

Hypophosphataemia treatments and more:

Hypophosphataemia (10,530 reports)

How severe was Hypophosphataemia and when was it recovered:

Hypophosphataemia in Hyzaar

Expand to all the drugs that have ingredients of hydrochlorothiazide; losartan potassium:

Hypophosphataemia and drugs with ingredients of hydrochlorothiazide; losartan potassium

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hyzaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypophosphataemia:

Hypophosphataemia (869 drugs)

Browse all the conditions that are associated with Hypophosphataemia:

Hypophosphataemia (781 conditions)

Related publications that referenced our studies

Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; losartan potassium (the active ingredients of Hyzaar) and Hyzaar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.