Ibu and Areflexia - a phase IV clinical study of FDA data

Summary:

Areflexia is reported as a side effect among people who take Ibu (ibuprofen), especially for people who are female, 20-29 old, also take Ambien, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Areflexia when taking Ibu. It is created by eHealthMe based on reports of 240,078 people who have side effects when taking Ibu from the FDA, and is updated regularly.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

What is Areflexia?

Areflexia (absence of a reflex) is found to be associated with 425 drugs and 728 conditions by eHealthMe. Check the latest studies of Areflexia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

240,078 people reported to have side effects when taking Ibu.
Among them, 62 people (0.03%) have Areflexia.

Among these 62 people:

What is the gender of people who have Areflexia when taking Ibu? *

female: 66.1 %
male: 33.9 %

What is the age of people who have Areflexia when taking Ibu? *

What are other drugs people take besides Ibu? *

What are other side effects people have besides Areflexia? *

Nausea (feeling of having an urge to vomit): 18 people, 29.03%
Stress And Anxiety: 16 people, 25.81%
Nausea And Vomiting: 16 people, 25.81%
Hypotension (abnormally low blood pressure): 16 people, 25.81%
Fatigue (feeling of tiredness): 15 people, 24.19%
Weakness: 15 people, 24.19%
Insomnia (sleeplessness): 13 people, 20.97%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 12 people, 19.35%
Overdose: 11 people, 17.74%
Dry Skin: 10 people, 16.13%

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 6.45%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 6.45%
Acne (skin problems that cause pimples): 3 people, 4.84%
Suicide Attempt: 3 people, 4.84%
Movement - Uncontrolled Or Slow: 2 people, 3.23%
Depression: 2 people, 3.23%
High Blood Pressure: 2 people, 3.23%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 3.23%
Metastases To Bone (cancer spreads to bone): 2 people, 3.23%
Tardive Dyskinesia (a disorder that involves involuntary movements): 2 people, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Ibu and have Areflexia?

- Check whether Areflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibu:

Ibu (246,531 reports)

Areflexia treatments and more:

Areflexia (3,364 reports)

Browse all side effects of Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Areflexia:

Areflexia (425 drugs)

Browse all the conditions that are associated with Areflexia:

Areflexia (728 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibu) and Ibu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.