1. Home
  2. Analysis
  3. Ibu
  4. Gingival-hyperplasia

Ibu and Gingival hyperplasia - a phase IV clinical study of FDA data

Summary:

Gingival hyperplasia is reported as a side effect among people who take Ibu (ibuprofen), especially for people who are female, 60+ old, also take Norvasc, and have High blood pressure.

The phase IV clinical study analyzes which people have Gingival hyperplasia when taking Ibu. It is created by eHealthMe based on reports of 240,078 people who have side effects when taking Ibu from the FDA, and is updated regularly.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

What is Gingival hyperplasia?

Gingival hyperplasia (overgrowth of gums) is found to be associated with 154 drugs and 263 conditions by eHealthMe. Check the latest studies of Gingival hyperplasia.

On Jul, 20, 2026

240,078 people reported to have side effects when taking Ibu.
Among them, 11 people (0.0%) have Gingival hyperplasia.

Could Ibu cause Gingival hyperplasia?

Among these 11 people:

What is the gender of people who have Gingival hyperplasia when taking Ibu? *

  • female: 63.64 %
  • male: 36.36 %

What is the age of people who have Gingival hyperplasia when taking Ibu? *

  • 0-1: 0.0 %
  • 2-9: 9.09 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 36.36 %
  • 60+: 54.55 %

What are other drugs people take besides Ibu? *

  1. Xalatan: 3 people, 27.27%
  2. Norvasc: 3 people, 27.27%
  3. Zometa: 1 person, 9.09%
  4. Vasotec: 1 person, 9.09%
  5. Triamterene And Hydrochlorothiazide: 1 person, 9.09%
  6. Triamterene: 1 person, 9.09%
  7. Periochip: 1 person, 9.09%
  8. Nifedipine: 1 person, 9.09%
  9. Naproxen: 1 person, 9.09%
  10. Ms Contin: 1 person, 9.09%

What are other side effects people have besides Gingival hyperplasia? *

  1. Gingivitis (inflammation of gums): 4 people, 36.36%
  2. Gingival Pain (gum pain): 3 people, 27.27%
  3. Gingival Bleeding (bleeding gums): 3 people, 27.27%
  4. Weight Decreased: 1 person, 9.09%
  5. Swelling: 1 person, 9.09%
  6. Oral Pain: 1 person, 9.09%
  7. Metaplasia (change in the type of adult cells in a tissue to a form abnormal for that tissue): 1 person, 9.09%
  8. Jaw Disorder (jaw disease): 1 person, 9.09%
  9. Gums - Swollen: 1 person, 9.09%
  10. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 1 person, 9.09%

What are the existing conditions these people have? *

  1. Multiple Allergies (allergy to multiple agents): 1 person, 9.09%
  2. Metastases To Bone (cancer spreads to bone): 1 person, 9.09%
  3. High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ibu and have Gingival hyperplasia?

- Check whether Gingival hyperplasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibu:

  • Ibu (246,531 reports)

Gingival hyperplasia treatments and more:

How severe was Gingival hyperplasia and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gingival hyperplasia:

Browse all the conditions that are associated with Gingival hyperplasia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibu) and Ibu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.