Ibu and Joint ankylosis - a phase IV clinical study of FDA data

Summary:

Joint ankylosis is reported as a side effect among people who take Ibu (ibuprofen), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cosentyx, and have Osteoarthritis.

The phase IV clinical study analyzes which people have Joint ankylosis when taking Ibu. It is created by eHealthMe based on reports of 240,078 people who have side effects when taking Ibu from the FDA, and is updated regularly.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.

What is Joint ankylosis?

Joint ankylosis (a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint) is found to be associated with 130 drugs and 307 conditions by eHealthMe. Check the latest studies of Joint ankylosis.

On Jul, 15, 2026

240,078 people reported to have side effects when taking Ibu.
Among them, 17 people (0.01%) have Joint ankylosis.

Among these 17 people:

How long have people been on Ibu when they have Joint ankylosis? *

What is the gender of people who have Joint ankylosis when taking Ibu? *

female: 53.33 %
male: 46.67 %

What is the age of people who have Joint ankylosis when taking Ibu? *

What are other drugs people take besides Ibu? *

What are other side effects people have besides Joint ankylosis? *

Joint Pain: 9 people, 52.94%
Fatigue (feeling of tiredness): 8 people, 47.06%
Fever: 6 people, 35.29%
Depression: 6 people, 35.29%
Fall: 6 people, 35.29%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 6 people, 35.29%
Pain In Extremity: 5 people, 29.41%
Joint Swelling: 5 people, 29.41%
Gait Disturbance: 5 people, 29.41%
Swelling: 5 people, 29.41%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 23.53%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 23.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.76%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 11.76%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 1 person, 5.88%
Neuralgia (pain in one or more nerves): 1 person, 5.88%
Indigestion: 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%
Herpes Zoster: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Ibu and have Joint ankylosis?

- Check whether Joint ankylosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibu:

Ibu (246,531 reports)

Browse all side effects of Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint ankylosis:

Joint ankylosis (130 drugs)

Browse all the conditions that are associated with Joint ankylosis:

Joint ankylosis (307 conditions)

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibu) and Ibu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.