Ibu and Lactic acidosis - a phase IV clinical study of FDA data
Summary:
Lactic acidosis is reported as a side effect among people who take Ibu (ibuprofen), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Type 2 diabetes.
The phase IV clinical study analyzes which people have Lactic acidosis when taking Ibu. It is created by eHealthMe based on reports of 240,078 people who have side effects when taking Ibu from the FDA, and is updated regularly.
What is Ibu?
Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.
What is Lactic acidosis?
Lactic acidosis (low ph in body tissues) is found to be associated with 995 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Lactic acidosis.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
240,078 people reported to have side effects when taking Ibu.
Among them, 743 people (0.31%) have Lactic acidosis.

Among these 743 people:
How long have people been on Ibu when they have Lactic acidosis? *
What is the gender of people who have Lactic acidosis when taking Ibu? *
What is the age of people who have Lactic acidosis when taking Ibu? *
What are other drugs people take besides Ibu? *
What are other side effects people have besides Lactic acidosis? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Ibu and have Lactic acidosis?
- Check whether Lactic acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Ibu:
- Ibu (246,531 reports)
Lactic acidosis treatments and more:
- Lactic acidosis (34,314 reports)
How severe was Lactic acidosis and when was it recovered:
Expand to all the drugs that have ingredients of ibuprofen:
- Lactic acidosis and drugs with ingredients of ibuprofen (804 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ibu:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Lactic acidosis:
- Lactic acidosis (995 drugs)
Browse all the conditions that are associated with Lactic acidosis:
- Lactic acidosis (1,281 conditions)
Related publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibu) and Ibu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Levothyroxine Sodium cause N-Terminal Prohormone Brain Natriuretic Peptide Increased? - 2 seconds ago
- Claritin-D and Aspirin drug interactions for women aged 50-59 - 18 seconds ago
- Non-Small Cell Lung Cancer Metastatic and Interstitial Lung Disease - 19 seconds ago
- Could Levothyroxine Sodium cause Herniated Nucleus Pulposus (Slipped Disk)? - 26 seconds ago
- Melatonin and Muscle Spasm for Men aged 40-49 - 31 seconds ago
- Melatonin and Muscle Spasms for Men aged 40-49 - 31 seconds ago
- Could Albuterol cause Cell Death? - 32 seconds ago
- Could Carafate cause Abdominal Pain Lower? - 40 seconds ago
- Could Cephalexin cause Dermatitis Bullous? - 42 seconds ago
- Could Advil Liqui-Gels cause Hypophagia? - 53 seconds ago