Imdur and Rales - a phase IV clinical study of FDA data

Summary:

Rales is reported as a side effect among people who take Imdur (isosorbide mononitrate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Lasix, and have Myocardial ischaemia.

The phase IV clinical study analyzes which people have Rales when taking Imdur. It is created by eHealthMe based on reports of 17,119 people who have side effects when taking Imdur from the FDA, and is updated regularly.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.

What is Rales?

Rales (an abnormal respiratory sound characterized by fine crackles) is found to be associated with 897 drugs and 946 conditions by eHealthMe. Check the latest studies of Rales.

On Jul, 20, 2026

17,119 people reported to have side effects when taking Imdur.
Among them, 60 people (0.35%) have Rales.

Among these 60 people:

How long have people been on Imdur when they have Rales? *

What is the gender of people who have Rales when taking Imdur? *

female: 51.67 %
male: 48.33 %

What is the age of people who have Rales when taking Imdur? *

What are other drugs people take besides Imdur? *

What are other side effects people have besides Rales? *

Dyspnea (difficult or laboured breathing): 36 people, 60.00%
Cardiac Failure Congestive: 34 people, 56.67%
Chest Pain: 29 people, 48.33%
Oedema Peripheral (superficial swelling): 28 people, 46.67%
Weakness: 22 people, 36.67%
Dizziness: 21 people, 35.00%
Hypotension (abnormally low blood pressure): 19 people, 31.67%
Pain: 17 people, 28.33%
Enlarged Heart: 17 people, 28.33%
Wheezing (a high-pitched whistling sound made while you breath): 17 people, 28.33%

What are the existing conditions these people have? *

Heart Disease: 6 people, 10.00%
Dyslipidaemia (abnormal amount of lipids): 6 people, 10.00%
Nephropathy (damage to or disease of a kidney): 6 people, 10.00%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 6 people, 10.00%
Cardiac Failure: 4 people, 6.67%
Gout (uric acid crystals building up in the body): 3 people, 5.00%
Vaginal Tumors: 3 people, 5.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 5.00%
Bipolar Disorder (mood disorder): 3 people, 5.00%
Pain In Extremity: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Imdur and have Rales?

- Check whether Rales is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imdur:

Imdur (17,367 reports)

Rales treatments and more:

Rales (9,085 reports)

Browse all side effects of Imdur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rales:

Rales (897 drugs)

Browse all the conditions that are associated with Rales:

Rales (946 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate (the active ingredients of Imdur) and Imdur (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.