Imitrex and Injection site urticaria - a phase IV clinical study of FDA data

Summary:

Injection site urticaria is reported as a side effect among people who take Imitrex (sumatriptan succinate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Humira, and have Crohn's disease.

The phase IV clinical study analyzes which people have Injection site urticaria when taking Imitrex. It is created by eHealthMe based on reports of 15,815 people who have side effects when taking Imitrex from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Injection site urticaria?

Injection site urticaria (rash of round, red welts on the skin at injection site) is found to be associated with 555 drugs and 612 conditions by eHealthMe. Check the latest studies of Injection site urticaria.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

15,815 people reported to have side effects when taking Imitrex.
Among them, 52 people (0.33%) have Injection site urticaria.

Could Imitrex cause Injection site urticaria?

Among these 52 people:

How long have people been on Imitrex when they have Injection site urticaria? *

What is the gender of people who have Injection site urticaria when taking Imitrex? *

female: 94 %
male: 6 %

What is the age of people who have Injection site urticaria when taking Imitrex? *

What are other drugs people take besides Imitrex? *

What are other side effects people have besides Injection site urticaria? *

Injection Site Pain: 14 people, 26.92%
Injection Site Erythema (redness at injection site): 12 people, 23.08%
Injection Site Haemorrhage (bleeding from injection site): 6 people, 11.54%
Fatigue (feeling of tiredness): 5 people, 9.62%
Injection Site Bruising: 5 people, 9.62%
Injection Site Pruritus (severe itching at injection site): 5 people, 9.62%
Injection Site Swelling: 4 people, 7.69%
Fainting (loss of consciousness and postural tone): 4 people, 7.69%
Injection Site Haematoma (localized swelling filled with blood at injection site): 4 people, 7.69%
Diarrhea: 4 people, 7.69%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 9.62%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.69%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 3.85%
Birth Control: 2 people, 3.85%
Asthma: 2 people, 3.85%
Tuberculin Test Positive: 1 person, 1.92%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 1.92%
Stress And Anxiety: 1 person, 1.92%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 1.92%
Mood Swings (an extreme or rapid change in mood): 1 person, 1.92%

* Approximation only. Some reports may have incomplete information.

Do you take Imitrex and have Injection site urticaria?

- Check whether Injection site urticaria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imitrex:

Imitrex (17,149 reports)

Browse all side effects of Imitrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site urticaria:

Injection site urticaria (555 drugs)

Browse all the conditions that are associated with Injection site urticaria:

Injection site urticaria (612 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate (the active ingredients of Imitrex) and Imitrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.