Imodium a-d and Mi - a phase IV clinical study of FDA data

Summary:

Mi is reported as a side effect among people who take Imodium a-d (loperamide hydrochloride), especially for people who are female, 60+ old, also take Coreg, and have Diabetes.

The phase IV clinical study analyzes which people have Mi when taking Imodium a-d. It is created by eHealthMe based on reports of 8,753 people who have side effects when taking Imodium a-d from the FDA, and is updated regularly.

What is Imodium a-d?

Imodium a-d has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 8,944 Imodium a-d users. Check the latest studies of Imodium a-d.

What is Mi?

Mi (myocardial infarction, heart attack) is found to be associated with 3,217 drugs and 3,278 conditions by eHealthMe. Check the latest studies of Mi.



On Jun, 11, 2026

8,753 people reported to have side effects when taking Imodium a-d.
Among them, 41 people (0.47%) have Mi.

Could Imodium a-d cause Mi?

Among these 41 people:

What is the gender of people who have Mi when taking Imodium a-d? *

  • female: 55 %
  • male: 45 %

What is the age of people who have Mi when taking Imodium a-d? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 15.62 %
  • 50-59: 18.75 %
  • 60+: 65.62 %

What are other drugs people take besides Imodium a-d? *

  1. Coreg: 7 people, 17.07%
  2. Tylenol: 6 people, 14.63%
  3. Compazine: 5 people, 12.20%
  4. Xanax: 5 people, 12.20%
  5. Lasix: 5 people, 12.20%
  6. Pantoprazole: 5 people, 12.20%
  7. Valium: 4 people, 9.76%
  8. Prevacid: 4 people, 9.76%
  9. Revlimid: 4 people, 9.76%
  10. Plavix: 4 people, 9.76%

What are other side effects people have besides Mi? *

  1. Chest Pain: 12 people, 29.27%
  2. Fatigue (feeling of tiredness): 9 people, 21.95%
  3. Nausea (feeling of having an urge to vomit): 8 people, 19.51%
  4. Dyspnea (difficult or laboured breathing): 7 people, 17.07%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 17.07%
  6. Urinary Tract Infection: 7 people, 17.07%
  7. Cardiac Failure Congestive: 7 people, 17.07%
  8. Stress And Anxiety: 7 people, 17.07%
  9. Nausea And Vomiting: 6 people, 14.63%
  10. Swallowing Difficulty: 6 people, 14.63%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 3 people, 7.32%
  2. Renal Cell Carcinoma (a kidney cancer): 3 people, 7.32%
  3. Diabetes: 3 people, 7.32%
  4. Pain: 2 people, 4.88%
  5. Hiv Infection: 2 people, 4.88%
  6. Hyperkalemia (damage to or disease of the kidney): 2 people, 4.88%
  7. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 4.88%
  8. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 2.44%
  9. Breast Cancer Female: 1 person, 2.44%
  10. Cluster Headache (one-sided head pain with tearing): 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium a-d and have Mi?

- Check whether Mi is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium a-d:

Mi treatments and more:

  • Mi (266,145 reports)

How severe was Mi and when was it recovered:

Expand to all the drugs that have ingredients of loperamide hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium a-d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mi:

  • Mi (3,217 drugs)

Browse all the conditions that are associated with Mi:

  • Mi (3,278 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium a-d) and Imodium a-d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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