Imodium a-d and Surgery - a phase IV clinical study of FDA data

Summary:

Surgery is reported as a side effect among people who take Imodium a-d (loperamide hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Surgery when taking Imodium a-d. It is created by eHealthMe based on reports of 8,753 people who have side effects when taking Imodium a-d from the FDA, and is updated regularly.

What is Imodium a-d?

Imodium a-d has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 8,944 Imodium a-d users. Check the latest studies of Imodium a-d.

What is Surgery?

Surgery is found to be associated with 1,476 drugs and 1,246 conditions by eHealthMe. Check the latest studies of Surgery.

On Jul, 25, 2026

8,753 people reported to have side effects when taking Imodium a-d.
Among them, 21 people (0.24%) have Surgery.

Among these 21 people:

How long have people been on Imodium a-d when they have Surgery? *

What is the gender of people who have Surgery when taking Imodium a-d? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Surgery when taking Imodium a-d? *

What are other drugs people take besides Imodium a-d? *

What are other side effects people have besides Surgery? *

Pain: 3 people, 14.29%
Respiratory Disorder (respiratory disease): 2 people, 9.52%
Femur Fracture: 2 people, 9.52%
Weight Increased: 2 people, 9.52%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 9.52%
Upper Respiratory Tract Infection: 2 people, 9.52%
Fainting (loss of consciousness and postural tone): 1 person, 4.76%
Headache (pain in head): 1 person, 4.76%
Furuncle (infection of the hair follicle): 1 person, 4.76%
Foot Deformity (functional disability of foot): 1 person, 4.76%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 28.57%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 9.52%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.76%
Overgrowth Bacterial (extra growth due to bacteria): 1 person, 4.76%
Nausea And Vomiting: 1 person, 4.76%
Nausea (feeling of having an urge to vomit): 1 person, 4.76%
Muscle Spasms (muscle contraction): 1 person, 4.76%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium a-d and have Surgery?

- Check whether Surgery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium a-d:

Imodium a-d (8,944 reports)

Surgery treatments and more:

Surgery (63,811 reports)

Browse all side effects of Imodium a-d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Surgery:

Surgery (1,476 drugs)

Browse all the conditions that are associated with Surgery:

Surgery (1,246 conditions)

Related publications that referenced our studies

Briggs P, Hawrylack H, Mooney R, "Inhaled peppermint oil for postop nausea in patients undergoing cardiac surgery", Nursing, 2016 Jul .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .
Briggs P, Hawrylack H, Mooney R, "Inhaled peppermint oil for postop nausea in patients undergoing cardiac surgery", Nursing, 2016 Jul .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium a-d) and Imodium a-d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.