Imodium and Ear buzzing - a phase IV clinical study of FDA data

Summary:

Ear buzzing is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Compazine, and have Malaria.

The phase IV clinical study analyzes which people have Ear buzzing when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Ear buzzing?

Ear buzzing is found to be associated with 2,445 drugs and 3,078 conditions by eHealthMe. Check the latest studies of Ear buzzing.



On Aug, 30, 2025

44,210 people reported to have side effects when taking Imodium.
Among them, 134 people (0.3%) have Ear buzzing.

Could Imodium cause Ear buzzing?

Among these 134 people:

How long have people been on Imodium when they have Ear buzzing? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ear buzzing when taking Imodium? *

  • female: 48.76 %
  • male: 51.24 %

What is the age of people who have Ear buzzing when taking Imodium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.96 %
  • 20-29: 0.98 %
  • 30-39: 21.57 %
  • 40-49: 10.78 %
  • 50-59: 18.63 %
  • 60+: 46.08 %

What are other drugs people take besides Imodium? *

  1. Ambien: 20 people, 14.93%
  2. Prednisone: 20 people, 14.93%
  3. Compazine: 20 people, 14.93%
  4. Metformin: 18 people, 13.43%
  5. Lipitor: 18 people, 13.43%
  6. Bactrim: 18 people, 13.43%
  7. Antivert: 16 people, 11.94%
  8. Valium: 16 people, 11.94%
  9. Biaxin: 16 people, 11.94%
  10. Lariam: 16 people, 11.94%

What are other side effects people have besides Ear buzzing? *

  1. Headache (pain in head): 57 people, 42.54%
  2. Dizziness: 53 people, 39.55%
  3. Nausea (feeling of having an urge to vomit): 51 people, 38.06%
  4. Fatigue (feeling of tiredness): 47 people, 35.07%
  5. High Blood Pressure: 40 people, 29.85%
  6. Joint Pain: 30 people, 22.39%
  7. Abdominal Pain: 29 people, 21.64%
  8. Pain Of Skin: 29 people, 21.64%
  9. Urinary Tract Infection: 26 people, 19.40%
  10. Insomnia (sleeplessness): 26 people, 19.40%

What are the existing conditions these people have? *

  1. Vestibular Disorder (disorders of the body's balance (vestibular) system in the inner ear): 16 people, 11.94%
  2. Enteritis Infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus): 16 people, 11.94%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 16 people, 11.94%
  4. Malaria (a parasitic disease due to mosquito bite): 16 people, 11.94%
  5. Neuropathy Peripheral (surface nerve damage): 14 people, 10.45%
  6. Ankylosing Spondylitis (type of arthritis affecting the spine): 13 people, 9.70%
  7. Swelling: 13 people, 9.70%
  8. Rosacea (a skin condition that causes facial redness): 13 people, 9.70%
  9. Urethral Cancer: 11 people, 8.21%
  10. Transitional Cell Carcinoma (cancer tumour inner most layer of urinary system): 11 people, 8.21%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Ear buzzing?

- Check whether Ear buzzing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Ear buzzing treatments and more:

How severe was Ear buzzing and when was it recovered:

Expand to all the drugs that have ingredients of loperamide hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Imodium side effects:

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ear buzzing:

Browse all the drugs that are associated with Ear buzzing:

Common conditions associated with Ear buzzing:

Browse all the conditions that are associated with Ear buzzing:


How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: