Imodium and Hyperthyroid - a phase IV clinical study of FDA data

Summary:

Hyperthyroid is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Renal cell carcinoma.

The phase IV clinical study analyzes which people have Hyperthyroid when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Hyperthyroid?

Hyperthyroid is found to be associated with 1,099 drugs and 1,420 conditions by eHealthMe. Check the latest studies of Hyperthyroid.



On Jun, 27, 2026

44,210 people reported to have side effects when taking Imodium.
Among them, 50 people (0.11%) have Hyperthyroid.

Could Imodium cause Hyperthyroid?

Among these 50 people:

How long have people been on Imodium when they have Hyperthyroid? *

  • < 1 month: 83.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperthyroid when taking Imodium? *

  • female: 48.98 %
  • male: 51.02 %

What is the age of people who have Hyperthyroid when taking Imodium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 9.3 %
  • 20-29: 0.0 %
  • 30-39: 4.65 %
  • 40-49: 6.98 %
  • 50-59: 32.56 %
  • 60+: 46.51 %

What are other drugs people take besides Imodium? *

  1. Acetaminophen: 8 people, 16.00%
  2. Zocor: 6 people, 12.00%
  3. Docetaxel: 6 people, 12.00%
  4. Tylenol: 6 people, 12.00%
  5. Zoladex: 6 people, 12.00%
  6. Prednisone: 5 people, 10.00%
  7. Tracleer: 5 people, 10.00%
  8. Camptosar: 5 people, 10.00%
  9. Remodulin: 5 people, 10.00%
  10. Fluorouracil: 5 people, 10.00%

What are other side effects people have besides Hyperthyroid? *

  1. Fatigue (feeling of tiredness): 14 people, 28.00%
  2. Weight Decreased: 11 people, 22.00%
  3. Abdominal Discomfort: 8 people, 16.00%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 16.00%
  5. Malaise (a feeling of general discomfort or uneasiness): 8 people, 16.00%
  6. Weakness: 7 people, 14.00%
  7. Dizziness: 6 people, 12.00%
  8. Abdominal Pain: 6 people, 12.00%
  9. High Blood Pressure: 5 people, 10.00%
  10. Pain In Extremity: 5 people, 10.00%

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 7 people, 14.00%
  2. Prostate Cancer Metastatic: 6 people, 12.00%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 8.00%
  4. Gastrointestinal Stromal Tumor: 3 people, 6.00%
  5. Depression: 3 people, 6.00%
  6. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 3 people, 6.00%
  7. Multiple Myeloma (cancer of the plasma cells): 3 people, 6.00%
  8. Gastric Cancer Stage Iv With Metastases (cancer cells have spread to distant organs): 3 people, 6.00%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 4.00%
  10. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Hyperthyroid?

- Check whether Hyperthyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Hyperthyroid treatments and more:

How severe was Hyperthyroid and when was it recovered:

Expand to all the drugs that have ingredients of loperamide hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroid:

Browse all the conditions that are associated with Hyperthyroid:


How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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