Imodium and Injection site irritation - a phase IV clinical study of FDA data

Summary:

Injection site irritation is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are female, 60+ old, also take Levothyroxine Sodium, and have Short-bowel syndrome.

The phase IV clinical study analyzes which people have Injection site irritation when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Injection site irritation?

Injection site irritation is found to be associated with 452 drugs and 511 conditions by eHealthMe. Check the latest studies of Injection site irritation.

On Jul, 18, 2026

44,210 people reported to have side effects when taking Imodium.
Among them, 15 people (0.03%) have Injection site irritation.

Could Imodium cause Injection site irritation?

Among these 15 people:

What is the gender of people who have Injection site irritation when taking Imodium? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Injection site irritation when taking Imodium? *

What are other drugs people take besides Imodium? *

Alprazolam: 6 people, 40.00%
Humira: 6 people, 40.00%
Lovenox: 6 people, 40.00%
Eliquis: 6 people, 40.00%
Pantoprazole Sodium: 6 people, 40.00%
Celexa: 6 people, 40.00%
Levothyroxine Sodium: 6 people, 40.00%
Xifaxan: 3 people, 20.00%
Dicyclomine Hydrochloride: 3 people, 20.00%
Prednisone: 2 people, 13.33%

What are other side effects people have besides Injection site irritation? *

Weight Decreased: 7 people, 46.67%
Abdominal Pain Upper: 6 people, 40.00%
Chills (felling of cold): 6 people, 40.00%
Dehydration (dryness resulting from the removal of water): 6 people, 40.00%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 6 people, 40.00%
Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 40.00%
Renal Disorder (kidney disease): 6 people, 40.00%
Gastrointestinal Stoma Complication (complication of an opening surgically made in digestive tract): 6 people, 40.00%
Hypersensitivity: 6 people, 40.00%
Tumor: 4 people, 26.67%

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 7 people, 46.67%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Injection site irritation?

- Check whether Injection site irritation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Imodium (45,092 reports)

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site irritation:

Injection site irritation (452 drugs)

Browse all the conditions that are associated with Injection site irritation:

Injection site irritation (511 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.