Imodium and Malabsorption - a phase IV clinical study of FDA data

Summary:

Malabsorption is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lomotil, and have High blood pressure.

The phase IV clinical study analyzes which people have Malabsorption when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,091 Imodium users. Check the latest studies of Imodium.

What is Malabsorption?

Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract) is found to be associated with 753 drugs and 1,080 conditions by eHealthMe. Check the latest studies of Malabsorption.

On Oct, 15, 2025

44,210 people reported to have side effects when taking Imodium.
Among them, 68 people (0.15%) have Malabsorption.

Among these 68 people:

How long have people been on Imodium when they have Malabsorption? *

What is the gender of people who have Malabsorption when taking Imodium? *

female: 74.51 %
male: 25.49 %

What is the age of people who have Malabsorption when taking Imodium? *

What are other drugs people take besides Imodium? *

What are other side effects people have besides Malabsorption? *

Umbilical Hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button): 18 people, 26.47%
Nausea And Vomiting: 18 people, 26.47%
Stress And Anxiety: 18 people, 26.47%
Nausea (feeling of having an urge to vomit): 17 people, 25.00%
Urinary Tract Infection: 16 people, 23.53%
Abdominal Pain Upper: 15 people, 22.06%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 15 people, 22.06%
Hypotension (abnormally low blood pressure): 14 people, 20.59%
Anaemia (lack of blood): 13 people, 19.12%
High Blood Pressure: 13 people, 19.12%

What are the existing conditions these people have? *

High Blood Pressure: 34 people, 50.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 7.35%
Nausea (feeling of having an urge to vomit): 3 people, 4.41%
Stress And Anxiety: 3 people, 4.41%
Weakness: 2 people, 2.94%
Depression: 2 people, 2.94%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 2.94%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 2.94%
High Blood Cholesterol: 2 people, 2.94%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Malabsorption?

- Check whether Malabsorption is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Imodium (45,091 reports)

Malabsorption treatments and more:

Malabsorption (8,910 reports)

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malabsorption:

Malabsorption (753 drugs)

Browse all the conditions that are associated with Malabsorption:

Malabsorption (1,080 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.