Imodium and Obliterative bronchiolitis - a phase IV clinical study of FDA data

Summary:

Obliterative bronchiolitis is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Dexilant, and have Headache.

The phase IV clinical study analyzes which people have Obliterative bronchiolitis when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Obliterative bronchiolitis?

Obliterative bronchiolitis (bronchiolar inflammation) is found to be associated with 164 drugs and 489 conditions by eHealthMe. Check the latest studies of Obliterative bronchiolitis.



On Jul, 04, 2026

44,210 people reported to have side effects when taking Imodium.
Among them, 12 people (0.03%) have Obliterative bronchiolitis.

Could Imodium cause Obliterative bronchiolitis?

Among these 12 people:

How long have people been on Imodium when they have Obliterative bronchiolitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Obliterative bronchiolitis when taking Imodium? *

  • female: 90 %
  • male: 10 %

What is the age of people who have Obliterative bronchiolitis when taking Imodium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 60 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 30 %
  • 50-59: 0.0 %
  • 60+: 10 %

What are other drugs people take besides Imodium? *

  1. Advil: 6 people, 50.00%
  2. Tylenol: 6 people, 50.00%
  3. Dexilant: 6 people, 50.00%
  4. Acetaminophen: 5 people, 41.67%
  5. Methylprednisolone Sodium Succinate: 5 people, 41.67%
  6. Fluconazole: 5 people, 41.67%
  7. Calcium Citrate: 5 people, 41.67%
  8. Breo Ellipta: 5 people, 41.67%
  9. Magnesium: 5 people, 41.67%
  10. Azathioprine: 5 people, 41.67%

What are other side effects people have besides Obliterative bronchiolitis? *

  1. Pneumonia: 12 people, 100.00%
  2. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 6 people, 50.00%
  3. Calculus Bladder (bladder stone): 6 people, 50.00%
  4. Bone Infarction (ischemic death of the cellular elements of the bone and marrow): 6 people, 50.00%
  5. High Blood Pressure: 6 people, 50.00%
  6. Erythema Multiforme (a type of hypersensitivity reaction): 6 people, 50.00%
  7. Oesophageal Stenosis (narrowing of oesophagus): 6 people, 50.00%
  8. Alanine Aminotransferase Increased: 6 people, 50.00%
  9. Candida Sepsis (candida in blood stream): 6 people, 50.00%
  10. Pancreatitis Chronic (chronic inflammation of pancreas): 6 people, 50.00%

What are the existing conditions these people have? *

  1. Headache (pain in head): 6 people, 50.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 41.67%
  3. Protein C Deficiency: 5 people, 41.67%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 41.67%
  5. Fever: 5 people, 41.67%
  6. Asthma: 5 people, 41.67%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 41.67%
  8. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Obliterative bronchiolitis?

- Check whether Obliterative bronchiolitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Obliterative bronchiolitis treatments and more:

How severe was Obliterative bronchiolitis and when was it recovered:

Expand to all the drugs that have ingredients of loperamide hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obliterative bronchiolitis:

Browse all the conditions that are associated with Obliterative bronchiolitis:


How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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