Imodium and Otitis - a phase IV clinical study of FDA data

Summary:

Otitis is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Oxycodone, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Otitis when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Otitis?

Otitis (ear infection) is found to be associated with 1,472 drugs and 1,815 conditions by eHealthMe. Check the latest studies of Otitis.

On Jan, 16, 2026

44,210 people reported to have side effects when taking Imodium.
Among them, 61 people (0.14%) have Otitis.

Among these 61 people:

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Otitis?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Imodium (45,092 reports)

Otitis treatments and more:

Otitis (36,446 reports)

How severe was Otitis and when was it recovered:

Otitis in Imodium

Expand to all the drugs that have ingredients of loperamide hydrochloride:

Otitis and drugs with ingredients of loperamide hydrochloride (141 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Imodium side effects:

Imodium side effect: Fatigue (feeling of tiredness) (4,286 reports)

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Otitis:

Browse all the drugs that are associated with Otitis:

Otitis (1,472 drugs)

Common conditions associated with Otitis:

Arthritis - rheumatoid: 5,464 reports
Rheumatoid arthritis: 5,460 reports
Psoriasis: 2,063 reports
Ileitis aggravated: 1,842 reports
Inflammatory bowel disease - crohn's disease: 1,840 reports
Psoriatic arthropathy: 1,662 reports
Multiple sclerosis aggravated: 1,514 reports
Multiple sclerosis: 1,507 reports
Immunodeficiency common variable: 1,281 reports
Chronic asthma: 1,197 reports

Browse all the conditions that are associated with Otitis:

Otitis (1,815 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.