Imodium and Spastic colon - a phase IV clinical study of FDA data

Summary:

Spastic colon is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Phenergan, and have High blood pressure.

The phase IV clinical study analyzes which people have Spastic colon when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Spastic colon?

Spastic colon (repeated abdominal pain and diarrhoea) is found to be associated with 2,246 drugs and 2,169 conditions by eHealthMe. Check the latest studies of Spastic colon.

On Apr, 24, 2026

44,210 people reported to have side effects when taking Imodium.
Among them, 234 people (0.53%) have Spastic colon.

Among these 234 people:

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Spastic colon?

- Check whether Spastic colon is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Imodium (45,092 reports)

Spastic colon treatments and more:

Spastic colon (49,237 reports)

How severe was Spastic colon and when was it recovered:

Spastic colon in Imodium

Expand to all the drugs that have ingredients of loperamide hydrochloride:

Spastic colon and drugs with ingredients of loperamide hydrochloride (369 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spastic colon:

Spastic colon (2,246 drugs)

Browse all the conditions that are associated with Spastic colon:

Spastic colon (2,169 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.