Imodium and Streptococcal bacteraemia - a phase IV clinical study of FDA data

Summary:

Streptococcal bacteraemia is reported as a side effect among people who take Imodium (loperamide hydrochloride), especially for people who are male, 60+ old, also take Benadryl, and have Graft versus host disease.

The phase IV clinical study analyzes which people have Streptococcal bacteraemia when taking Imodium. It is created by eHealthMe based on reports of 44,210 people who have side effects when taking Imodium from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Streptococcal bacteraemia?

Streptococcal bacteraemia (a bacterial infection of blood) is found to be associated with 236 drugs and 316 conditions by eHealthMe. Check the latest studies of Streptococcal bacteraemia.

On Jul, 19, 2026

44,210 people reported to have side effects when taking Imodium.
Among them, 11 people (0.02%) have Streptococcal bacteraemia.

Could Imodium cause Streptococcal bacteraemia?

Among these 11 people:

What is the gender of people who have Streptococcal bacteraemia when taking Imodium? *

female: 50 %
male: 50 %

What is the age of people who have Streptococcal bacteraemia when taking Imodium? *

What are other drugs people take besides Imodium? *

What are other side effects people have besides Streptococcal bacteraemia? *

Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 5 people, 45.45%
Intra-Abdominal Haemorrhage (intra-abdominal bleeding): 4 people, 36.36%
Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity): 4 people, 36.36%
Pneumatosis Intestinalis (air or gas in an intestine): 4 people, 36.36%
High Blood Pressure: 3 people, 27.27%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 18.18%
Flatulence (flatus expelled through the anus): 1 person, 9.09%
Fatigue (feeling of tiredness): 1 person, 9.09%
Drowsiness: 1 person, 9.09%
Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 1 person, 9.09%

What are the existing conditions these people have? *

Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 36.36%
Type 2 Diabetes: 3 people, 27.27%
Pain: 3 people, 27.27%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 27.27%
High Blood Pressure: 3 people, 27.27%
Infusion Related Reaction: 3 people, 27.27%
Depression: 3 people, 27.27%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 27.27%
Dyslipidaemia (abnormal amount of lipids): 3 people, 27.27%
Asthma: 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and have Streptococcal bacteraemia?

- Check whether Streptococcal bacteraemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imodium:

Imodium (45,092 reports)

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Streptococcal bacteraemia:

Streptococcal bacteraemia (236 drugs)

Browse all the conditions that are associated with Streptococcal bacteraemia:

Streptococcal bacteraemia (316 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride (the active ingredients of Imodium) and Imodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.