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Imuran and Herpes simplex - a phase IV clinical study of FDA data

Summary:

Herpes simplex is reported as a side effect among people who take Imuran (azathioprine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Herpes simplex when taking Imuran. It is created by eHealthMe based on reports of 34,190 people who have side effects when taking Imuran from the FDA, and is updated regularly.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

What is Herpes simplex?

Herpes simplex (herpes simplex is a common viral infection) is found to be associated with 713 drugs and 896 conditions by eHealthMe. Check the latest studies of Herpes simplex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

34,190 people reported to have side effects when taking Imuran.
Among them, 16 people (0.05%) have Herpes simplex.

Could Imuran cause Herpes simplex?

Among these 16 people:

How long have people been on Imuran when they have Herpes simplex? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Herpes simplex when taking Imuran? *

  • female: 56.25 %
  • male: 43.75 %

What is the age of people who have Herpes simplex when taking Imuran? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 10 %
  • 20-29: 0.0 %
  • 30-39: 10 %
  • 40-49: 10 %
  • 50-59: 30 %
  • 60+: 40 %

What are other drugs people take besides Imuran? *

  1. Prednisone: 7 people, 43.75%
  2. Remicade: 5 people, 31.25%
  3. Flagyl: 3 people, 18.75%
  4. Synthroid: 3 people, 18.75%
  5. Humira: 3 people, 18.75%
  6. Cipro: 2 people, 12.50%
  7. Vancomycin: 2 people, 12.50%
  8. Tylenol: 2 people, 12.50%
  9. Allopurinol: 2 people, 12.50%
  10. Lasix: 2 people, 12.50%

What are other side effects people have besides Herpes simplex? *

  1. Chest Pain: 3 people, 18.75%
  2. Renal Failure Acute On Chronic (rapid or long lasting kidney failure): 2 people, 12.50%
  3. Septicaemia Serratia (blood infection by bacteria): 2 people, 12.50%
  4. Nausea (feeling of having an urge to vomit): 2 people, 12.50%
  5. Necrosis (the death of body tissue): 2 people, 12.50%
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 12.50%
  7. Cellulitis (infection under the skin): 2 people, 12.50%
  8. Lung Consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces): 2 people, 12.50%
  9. Carotid Artery Stenosis (narrowing of carotid artery): 2 people, 12.50%
  10. Joint Pain: 2 people, 12.50%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
  2. Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.25%
  3. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 6.25%
  4. Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Imuran and have Herpes simplex?

- Check whether Herpes simplex is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imuran:

Herpes simplex treatments and more:

How severe was Herpes simplex and when was it recovered:

Expand to all the drugs that have ingredients of azathioprine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herpes simplex:

Browse all the conditions that are associated with Herpes simplex:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on azathioprine (the active ingredients of Imuran) and Imuran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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