1. Home
  2. Analysis
  3. Imuran
  4. Mental-impairment

Imuran and Mental impairment - a phase IV clinical study of FDA data

Summary:

Mental impairment is reported as a side effect among people who take Imuran (azathioprine), especially for people who are female, 60+ old, also take Prednisone, and have Lambert-eaton syndrome.

The phase IV clinical study analyzes which people have Mental impairment when taking Imuran. It is created by eHealthMe based on reports of 34,190 people who have side effects when taking Imuran from the FDA, and is updated regularly.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

What is Mental impairment?

Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition) is found to be associated with 1,336 drugs and 1,316 conditions by eHealthMe. Check the latest studies of Mental impairment.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

34,190 people reported to have side effects when taking Imuran.
Among them, 24 people (0.07%) have Mental impairment.

Could Imuran cause Mental impairment?

Among these 24 people:

What is the gender of people who have Mental impairment when taking Imuran? *

  • female: 68.18 %
  • male: 31.82 %

What is the age of people who have Mental impairment when taking Imuran? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 10.53 %
  • 20-29: 5.26 %
  • 30-39: 10.53 %
  • 40-49: 10.53 %
  • 50-59: 15.79 %
  • 60+: 47.37 %

What are other drugs people take besides Imuran? *

  1. Prednisone: 13 people, 54.17%
  2. Fish Oil: 4 people, 16.67%
  3. Cellcept: 4 people, 16.67%
  4. Calcium: 4 people, 16.67%
  5. Asacol: 4 people, 16.67%
  6. Estradiol: 3 people, 12.50%
  7. Firdapse: 3 people, 12.50%
  8. Loperamide Hydrochloride: 3 people, 12.50%
  9. Gabapentin: 3 people, 12.50%
  10. Nexium: 3 people, 12.50%

What are other side effects people have besides Mental impairment? *

  1. Weakness: 6 people, 25.00%
  2. Dyspnea (difficult or laboured breathing): 6 people, 25.00%
  3. Fatigue (feeling of tiredness): 5 people, 20.83%
  4. Limb Discomfort (discomfort in leg): 4 people, 16.67%
  5. Malaise (a feeling of general discomfort or uneasiness): 4 people, 16.67%
  6. Electrolyte Imbalance: 3 people, 12.50%
  7. Accidental Exposure: 3 people, 12.50%
  8. Fall: 3 people, 12.50%
  9. Balance Disorder: 3 people, 12.50%
  10. Drug Ineffective: 3 people, 12.50%

What are the existing conditions these people have? *

  1. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 3 people, 12.50%
  2. High Blood Pressure: 1 person, 4.17%
  3. Asthma: 1 person, 4.17%
  4. Blood Pressure Abnormal: 1 person, 4.17%
  5. Cardiac Disorder: 1 person, 4.17%
  6. Depression: 1 person, 4.17%
  7. Diarrhea: 1 person, 4.17%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 4.17%
  9. Fungal Infection: 1 person, 4.17%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Imuran and have Mental impairment?

- Check whether Mental impairment is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imuran:

Mental impairment treatments and more:

How severe was Mental impairment and when was it recovered:

Expand to all the drugs that have ingredients of azathioprine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mental impairment:

Browse all the conditions that are associated with Mental impairment:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on azathioprine (the active ingredients of Imuran) and Imuran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.