Increlex and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Increlex (mecasermin recombinant), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Norditropin, and have Body height below normal.

The phase IV clinical study analyzes which people have Pain when taking Increlex. It is created by eHealthMe based on reports of 1,007 people who have side effects when taking Increlex from the FDA, and is updated regularly.

What is Increlex?

Increlex has active ingredients of mecasermin recombinant. eHealthMe is studying from 1,010 Increlex users. Check the latest studies of Increlex.

What is Pain?

Pain is found to be associated with 3,806 drugs and 5,872 conditions by eHealthMe. Check the latest studies of Pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

1,007 people reported to have side effects when taking Increlex.
Among them, 18 people (1.79%) have Pain.

Among these 18 people:

How long have people been on Increlex when they have Pain? *

What is the gender of people who have Pain when taking Increlex? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Pain when taking Increlex? *

What are other drugs people take besides Increlex? *

What are other side effects people have besides Pain? *

Blood Glucose Decreased: 4 people, 22.22%
Scoliosis (a medical condition in which a person's spine is curved from side to side): 4 people, 22.22%
Joint Pain: 3 people, 16.67%
Headache (pain in head): 3 people, 16.67%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 3 people, 16.67%
Restrictive Pulmonary Disease (reduction in total lung capacity): 3 people, 16.67%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 3 people, 16.67%
Necrosis (the death of body tissue): 3 people, 16.67%
Shock Haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding): 3 people, 16.67%
Overdose: 3 people, 16.67%

What are the existing conditions these people have? *

Body Height Below Normal: 4 people, 22.22%
Insulin-Like Growth Factor Decreased: 2 people, 11.11%
High Blood Pressure: 2 people, 11.11%
Thyroid Diseases: 1 person, 5.56%
Foetal Growth Restriction (poor growth of a baby while in the mother's womb during pregnancy): 1 person, 5.56%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.56%
Birth Control: 1 person, 5.56%
Cardiac Disorder: 1 person, 5.56%
Failure To Thrive (inadequate weight gain and physical growth in children): 1 person, 5.56%
Growth Retardation (delayed growth): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Increlex and have Pain?

- Check whether Pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Increlex:

Increlex (1,010 reports)

Pain treatments and more:

Pain (1,140,596 reports)

Browse all side effects of Increlex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

Pain (3,806 drugs)

Browse all the conditions that are associated with Pain:

Pain (5,872 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mecasermin recombinant (the active ingredients of Increlex) and Increlex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.