Inderal and International normalised ratio increased - a phase IV clinical study of FDA data

Summary:

International normalised ratio increased is reported as a side effect among people who take Inderal (propranolol hydrochloride), especially for people who are female, 60+ old, also take Coumadin, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have International normalised ratio increased when taking Inderal. It is created by eHealthMe based on reports of 15,491 people who have side effects when taking Inderal from the FDA, and is updated regularly.

What is Inderal?

Inderal has active ingredients of propranolol hydrochloride. It is often used in migraine. eHealthMe is studying from 16,771 Inderal users. Check the latest studies of Inderal.

What is International normalised ratio increased?

International normalised ratio increased is found to be associated with 1,333 drugs and 1,727 conditions by eHealthMe. Check the latest studies of International normalised ratio increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

15,491 people reported to have side effects when taking Inderal.
Among them, 48 people (0.31%) have International normalised ratio increased.

Could Inderal cause International normalised ratio increased?

Among these 48 people:

What is the gender of people who have International normalised ratio increased when taking Inderal? *

female: 66.67 %
male: 33.33 %

What is the age of people who have International normalised ratio increased when taking Inderal? *

What are other drugs people take besides Inderal? *

What are other side effects people have besides International normalised ratio increased? *

Hypotension (abnormally low blood pressure): 8 people, 16.67%
Pneumonia: 7 people, 14.58%
Haemoglobin Decreased: 7 people, 14.58%
Pulmonary Embolism (blockage of the main artery of the lung): 7 people, 14.58%
Haematocrit Decreased: 7 people, 14.58%
Blood Glucose Increased: 6 people, 12.50%
Weakness: 6 people, 12.50%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 10.42%
Oedema Peripheral (superficial swelling): 5 people, 10.42%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 5 people, 10.42%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 10.42%
Birth Control: 4 people, 8.33%
Arrhythmias (irregular heartbeat): 2 people, 4.17%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.17%
Type 2 Diabetes: 1 person, 2.08%
Hepatitis C: 1 person, 2.08%
Appetite Disorder (abnormal eating habits): 1 person, 2.08%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 2.08%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 1 person, 2.08%
Constipation: 1 person, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Inderal and have International normalised ratio increased?

- Check whether International normalised ratio increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Inderal:

Inderal (16,771 reports)

International normalised ratio increased treatments and more:

International normalised ratio increased (40,071 reports)

How severe was International normalised ratio increased and when was it recovered:

International normalised ratio increased in Inderal

Expand to all the drugs that have ingredients of propranolol hydrochloride:

International normalised ratio increased and drugs with ingredients of propranolol hydrochloride (152 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Inderal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with International normalised ratio increased:

International normalised ratio increased (1,333 drugs)

Browse all the conditions that are associated with International normalised ratio increased:

International normalised ratio increased (1,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on propranolol hydrochloride (the active ingredients of Inderal) and Inderal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.