Innohep and Nephrotic syndrome - a phase IV clinical study of FDA data

Summary:

Nephrotic syndrome is reported as a side effect among people who take Innohep (tinzaparin sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Hypocalcaemia.

The phase IV clinical study analyzes which people have Nephrotic syndrome when taking Innohep. It is created by eHealthMe based on reports of 9,220 people who have side effects when taking Innohep from the FDA, and is updated regularly.

What is Innohep?

Innohep has active ingredients of tinzaparin sodium. eHealthMe is studying from 9,243 Innohep users. Check the latest studies of Innohep.

What is Nephrotic syndrome?

Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema) is found to be associated with 626 drugs and 1,072 conditions by eHealthMe. Check the latest studies of Nephrotic syndrome.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 17, 2026

9,220 people reported to have side effects when taking Innohep.
Among them, 19 people (0.21%) have Nephrotic syndrome.

Could Innohep cause Nephrotic syndrome?

Among these 19 people:

How long have people been on Innohep when they have Nephrotic syndrome? *

  • < 1 month: 85.71 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 14.29 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Nephrotic syndrome when taking Innohep? *

  • female: 11.11 %
  • male: 88.89 %

What is the age of people who have Nephrotic syndrome when taking Innohep? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 21.05 %
  • 60+: 78.95 %

What are other drugs people take besides Innohep? *

  1. Carfilzomib: 12 people, 63.16%
  2. Lenalidomide: 12 people, 63.16%
  3. Zometa: 12 people, 63.16%
  4. Nebivolol Hydrochloride: 10 people, 52.63%
  5. Acetaminophen: 8 people, 42.11%
  6. Aspirin: 8 people, 42.11%
  7. Nexium: 8 people, 42.11%
  8. Dexamethasone: 8 people, 42.11%
  9. Sodium Chloride: 6 people, 31.58%
  10. Omeprazole: 6 people, 31.58%

What are other side effects people have besides Nephrotic syndrome? *

  1. White Blood Cell Count Increased: 2 people, 10.53%
  2. Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 2 people, 10.53%
  3. C-Reactive Protein Increased: 2 people, 10.53%
  4. Dyspnea (difficult or laboured breathing): 2 people, 10.53%
  5. Fatigue (feeling of tiredness): 2 people, 10.53%
  6. Fever: 2 people, 10.53%
  7. General Physical Health Deterioration (weak health status): 2 people, 10.53%
  8. Glomerulonephropathy (any noninflammatory disease of the renal glomeruli): 2 people, 10.53%
  9. Haematuria (presence of blood in urine): 2 people, 10.53%
  10. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 2 people, 10.53%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 63.16%
  2. Renal Impairment (severely reduced kidney function): 12 people, 63.16%
  3. Multiple Myeloma (cancer of the plasma cells): 12 people, 63.16%
  4. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 12 people, 63.16%
  5. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 9 people, 47.37%
  6. Adverse Event: 8 people, 42.11%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 8 people, 42.11%
  8. Dehydration (dryness resulting from the removal of water): 3 people, 15.79%
  9. Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 10.53%
  10. Colitis (inflammation of colon): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Innohep and have Nephrotic syndrome?

- Check whether Nephrotic syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Innohep:

Nephrotic syndrome treatments and more:

How severe was Nephrotic syndrome and when was it recovered:

Expand to all the drugs that have ingredients of tinzaparin sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Innohep:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephrotic syndrome:

Browse all the conditions that are associated with Nephrotic syndrome:


How the study uses the data?

The study uses data from the FDA. It is based on tinzaparin sodium (the active ingredients of Innohep) and Innohep (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: