Insulin and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Insulin (insulin pork), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Entresto, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Insulin. It is created by eHealthMe based on reports of 49,622 people who have side effects when taking Insulin from the FDA, and is updated regularly.

What is Insulin?

Insulin has active ingredients of insulin pork. It is often used in diabetes. eHealthMe is studying from 50,203 Insulin users. Check the latest studies of Insulin.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 680 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jul, 15, 2026

49,622 people reported to have side effects when taking Insulin.
Among them, 42 people (0.08%) have Diastolic dysfunction.

Could Insulin cause Diastolic dysfunction?

Among these 42 people:

How long have people been on Insulin when they have Diastolic dysfunction? *

What is the gender of people who have Diastolic dysfunction when taking Insulin? *

female: 22.5 %
male: 77.5 %

What is the age of people who have Diastolic dysfunction when taking Insulin? *

What are other drugs people take besides Insulin? *

What are other side effects people have besides Diastolic dysfunction? *

Dyspnea (difficult or laboured breathing): 31 people, 73.81%
Tricuspid Valve Incompetence (inefficient heart valve): 25 people, 59.52%
Anaemia (lack of blood): 25 people, 59.52%
Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 24 people, 57.14%
High Blood Pressure: 24 people, 57.14%
Blood Creatinine Increased: 24 people, 57.14%
Mitral Valve Incompetence (inefficient heart valve): 23 people, 54.76%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 23 people, 54.76%
C-Reactive Protein Increased: 22 people, 52.38%
Thrombocytopenia (decrease of platelets in blood): 22 people, 52.38%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 11.90%
High Blood Pressure: 4 people, 9.52%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 7.14%
Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased): 2 people, 4.76%
Cardiac Failure: 2 people, 4.76%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.76%
Dyspnea (difficult or laboured breathing): 2 people, 4.76%
Constipation: 2 people, 4.76%
Chronic Kidney Disease: 2 people, 4.76%
Cardiac Disorder: 2 people, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Insulin and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Insulin:

Insulin (50,203 reports)

Browse all side effects of Insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (680 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on insulin pork (the active ingredients of Insulin) and Insulin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.