Intuniv and Muscle twitching - a phase IV clinical study of FDA data

Summary:

Muscle twitching is reported as a side effect among people who take Intuniv (guanfacine hydrochloride), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Vyvanse, and have Irritable bowel syndrome.

The phase IV clinical study analyzes which people have Muscle twitching when taking Intuniv. It is created by eHealthMe based on reports of 3,469 people who have side effects when taking Intuniv from the FDA, and is updated regularly.

What is Intuniv?

Intuniv has active ingredients of guanfacine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 3,959 Intuniv users. Check the latest studies of Intuniv.

What is Muscle twitching?

Muscle twitching is found to be associated with 1,248 drugs and 1,900 conditions by eHealthMe. Check the latest studies of Muscle twitching.

On Apr, 25, 2026

3,469 people reported to have side effects when taking Intuniv.
Among them, 19 people (0.55%) have Muscle twitching.

Among these 19 people:

How long have people been on Intuniv when they have Muscle twitching? *

What is the gender of people who have Muscle twitching when taking Intuniv? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Muscle twitching when taking Intuniv? *

What are other drugs people take besides Intuniv? *

Vyvanse: 5 people, 26.32%
Concerta: 3 people, 15.79%
Abilify: 3 people, 15.79%
Trileptal: 2 people, 10.53%
Risperidone: 2 people, 10.53%
Allegra: 2 people, 10.53%
Lisdexamfetamine Dimesylate: 2 people, 10.53%
Linzess: 2 people, 10.53%
Fluoxetine: 1 person, 5.26%
Advair Hfa: 1 person, 5.26%

What are other side effects people have besides Muscle twitching? *

Muscle Spasms (muscle contraction): 4 people, 21.05%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 15.79%
Chest Pain: 3 people, 15.79%
Excessive Eye Blinking (excessive blinking is dry eyes): 3 people, 15.79%
Insomnia (sleeplessness): 2 people, 10.53%
Depressed Mood: 2 people, 10.53%
Weakness: 2 people, 10.53%
Itching: 2 people, 10.53%
Eye Pain: 2 people, 10.53%
Erection Problems: 2 people, 10.53%

What are the existing conditions these people have? *

Seasonal Allergy (allergic condition due to certain season): 2 people, 10.53%
Irritable Bowel Syndrome: 2 people, 10.53%
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 1 person, 5.26%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 5.26%
Primary Immunodeficiency Syndrome: 1 person, 5.26%
Immune System Disorder: 1 person, 5.26%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.26%
Depression: 1 person, 5.26%
Bipolar Disorder (mood disorder): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Intuniv and have Muscle twitching?

- Check whether Muscle twitching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Intuniv:

Intuniv (3,959 reports)

Muscle twitching treatments and more:

Muscle twitching (29,030 reports)

Browse all side effects of Intuniv:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle twitching:

Muscle twitching (1,248 drugs)

Browse all the conditions that are associated with Muscle twitching:

Muscle twitching (1,900 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on guanfacine hydrochloride (the active ingredients of Intuniv) and Intuniv (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.